Reconstruction of Optical Properties in Turbid Media: Omitting the Need of the Collimated Transmission for an Integrating Sphere Setup.

Currently, the most reliable approach to reconstruct optical properties, namely absorption coefficient, reduced scattering coefficient, scattering coefficient and asymmetry factor, of turbid media is through inverse Monte Carlo simulation. To determine these optical properties, three measurements are required: total transmission, total reflection and collimated transmission. However, the accurate determination of the collimated transmission is very difficult. To overcome the difficulty of measuring the collimated transmission, it is proposed to measure the total transmission and total reflection of the same sample with two different thicknesses instead. To prove this alternative solution, machine learning is used to prove that the repeated measurement for two different thicknesses carries all the necessary information. As a result, all four optical properties can be measured with high accuracy, particularly for interpolation problems where the test data fall within the range of the training data. For extrapolation problems, high accuracy can be achieved in the determination of at least the absorption coefficient, reduced scattering coefficient and scattering coefficient. Hence, these results allow that in the future, an easier and therefore more precise reconstruction of the optical properties is possible, potentially even with inverse Monte Carlo simulations as the current standard.