Evidence map›Paper›PMID 39123740›Full record

ArticleAnimals : an open access journal from MDPI2024

Resveratrol Enhances Antioxidant and Anti-Apoptotic Capacities in Chicken Primordial Germ Cells through m6A Methylation: A Preliminary Investigation.

Yanzhao Qiao, Gengsheng Xiao, Xiaohua Zhu, Jun Wen, Yonghui Bu, Xinheng Zhang, Jie Kong, Yinshan Bai, Qingmei Xie

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. NPoultry science · 2026
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yanzhao QiaoState Key Laboratory of Swine and Poultry Breeding Industry & Heyuan Branch, Guangdong Provincial Laboratory of Lingnan Modern Agricultural Science and Technology, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
Gengsheng XiaoState Key Laboratory of Swine and Poultry Breeding Industry & Heyuan Branch, Guangdong Provincial Laboratory of Lingnan Modern Agricultural Science and Technology, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0002-9444-1223
Xiaohua ZhuGuangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Jun WenGuangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Yonghui BuCollege of Animal Science, South China Agricultural University, Guangzhou 510642, China.
Xinheng ZhangState Key Laboratory of Swine and Poultry Breeding Industry & Heyuan Branch, Guangdong Provincial Laboratory of Lingnan Modern Agricultural Science and Technology, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0002-3232-4929
Jie KongState Key Laboratory of Swine and Poultry Breeding Industry & Heyuan Branch, Guangdong Provincial Laboratory of Lingnan Modern Agricultural Science and Technology, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
Yinshan BaiGuangdong Academy of Agricultural Sciences, Guangzhou 510640, China.ORCID 0000-0002-6482-0281
Qingmei XieState Key Laboratory of Swine and Poultry Breeding Industry & Heyuan Branch, Guangdong Provincial Laboratory of Lingnan Modern Agricultural Science and Technology, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.

Funding

China Agriculture Research System of MOF and MARA CARS-42-13Guangdong Provincial Key R&D Program 2020B020222001, 2019B020218004Heyuan Branch, Guangdong Laboratory for Lingnan Modern Agriculture Project DT20220003Provincial Science and Technology Special Fund Project for Zhongshan City (major special project + Task list management mode) 2021sdr003the construction project of modern agricultural science and technology innovation alliance in Guangdong province 2023KJ128, 2022KJ128, 2021KJ128, 2020KJ128the Guangdong Basic and Applied Basic Research Foundation 2023A1515010584the Natural Science Foundation of Guangzhou 2023A04J1461the Science and Technology Program of Guangdong province, China 2020B1212060060the Special Project of National Modern Agricultural Industrial Technology System CARS-41
6 · The paper itself

Abstract

Avian primordial germ cells (PGCs) are essential in avian transgenic research, germplasm conservation, and disease resistance breeding. However, cultured PGCs are prone to fragmentation and apoptosis, regulated at transcriptional and translational levels, with N6-methyladenosine (m6A) being the most common mRNA modification. Resveratrol (RSV) is known for its antioxidant and anti-apoptotic properties, but its effects on PGCs and the underlying mechanisms are not well understood. This study shows that RSV supplementation in cultured PGCs improves cell morphology, significantly enhances total antioxidant capacity (

Indexed as

antioxidantapoptosism6A methylationprimordial germ cellsresveratrol

Identifiers

PMID39123740
PMCPMC11311097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.