Evidence map›Paper›PMID 39123599›Full record

ReviewFoods (Basel, Switzerland)2024

Bacterial Degradation of Antinutrients in Foods: The Genomic Insight.

Alexander Arsov, Lidia Tsigoriyna, Daniela Batovska, Nadya Armenova, Wanmeng Mu, Wenli Zhang, Kaloyan Petrov, Penka Petrova

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Probiotics and Fermented Foods in Human Nutrition.Molecules (Basel, Switzerland) · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Biodiversity and genetic improvement ofFrontiers in plant science · 2026
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Antioxidants (Basel, Switzerland) · 2025
    Review
  15. Review
  16. Article
  17. Review
  18. Frontiers in nutrition · 2025
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander ArsovInstitute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0003-4733-9530
Lidia TsigoriynaInstitute of Chemical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0001-6123-2719
Daniela BatovskaInstitute of Chemical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Nadya ArmenovaInstitute of Chemical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0002-4552-1710
Wanmeng MuState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China.
Wenli ZhangState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China.
Kaloyan PetrovInstitute of Chemical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0001-9197-0894
Penka PetrovaInstitute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0001-7356-5799

Funding

National Science Program "Security and Defense" approved by the Council of Ministers of the Re-public of Bulgaria decision of No. 731/21.10.2021
6 · The paper itself

Abstract

Antinutrients, also known as anti-nutritional factors (ANFs), are compounds found in many plant-based foods that can limit the bioavailability of nutrients or can act as precursors to toxic substances. ANFs have controversial effects on human health, depending mainly on their concentration. While the positive effects of these compounds are well documented, the dangers they pose and the approaches to avoid them have not been discussed to the same extent. There is no dispute that many ANFs negatively alter the absorption of vitamins, minerals, and proteins in addition to inhibiting some enzyme activities, thus negatively affecting the bioavailability of nutrients in the human body. This review discusses the chemical properties, plant bioavailability, and deleterious effects of anti-minerals (phytates and oxalates), glycosides (cyanogenic glycosides and saponins), polyphenols (tannins), and proteinaceous ANFs (enzyme inhibitors and lectins). The focus of this study is on the possibility of controlling the amount of ANF in food through fermentation. An overview of the most common biochemical pathways for their microbial reduction is provided, showing the genetic basis of these phenomena, including the active enzymes, the optimal conditions of action, and some data on the regulation of their synthesis.

Indexed as

antinutrientscyanogenic glycosidesfermentationlectinsoxalatesphytic acidprotease inhibitorssaponinstannins

Identifiers

PMID39123599
PMCPMC11311503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.