Evidence map›Paper›PMID 39123398›Full record

ArticleCancers2024

Analysis of Molecular Imaging and Laboratory Baseline Biomarkers in PSMA-RLT: Whole-Body Total Lesion PSMA (TLP) Predicts Overall Survival.

Connor Hein, Caroline Burgard, Arne Blickle, Moritz B Bastian, Stephan Maus, Andrea Schaefer-Schuler, Manuela A Hoffmann, Mathias Schreckenberger, Samer Ezziddin, Florian Rosar

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Quantitative PSMA PET Biomarkers for Predicting Response toJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Pooled it
  3. Baseline PSMA PET/CT Biomarkers for Patient Selection in [Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Connor HeinDepartment of Nuclear Medicine, Saarland University-Medical Center, 66421 Homburg, Germany.
Caroline BurgardDepartment of Nuclear Medicine, Saarland University-Medical Center, 66421 Homburg, Germany.ORCID 0000-0003-1522-8860
Arne BlickleDepartment of Nuclear Medicine, Saarland University-Medical Center, 66421 Homburg, Germany.
Moritz B BastianDepartment of Nuclear Medicine, Saarland University-Medical Center, 66421 Homburg, Germany.ORCID 0009-0008-2106-9548
Stephan MausDepartment of Nuclear Medicine, Saarland University-Medical Center, 66421 Homburg, Germany.ORCID 0000-0003-1679-8080
Andrea Schaefer-SchulerDepartment of Nuclear Medicine, Saarland University-Medical Center, 66421 Homburg, Germany.
Manuela A HoffmannDepartment of Nuclear Medicine, Johannes Gutenberg University, 55101 Mainz, Germany.ORCID 0000-0002-8867-5525
Mathias SchreckenbergerDepartment of Nuclear Medicine, Johannes Gutenberg University, 55101 Mainz, Germany.
Samer EzziddinDepartment of Nuclear Medicine, Saarland University-Medical Center, 66421 Homburg, Germany.ORCID 0000-0003-4110-3375
Florian RosarDepartment of Nuclear Medicine, Saarland University-Medical Center, 66421 Homburg, Germany.ORCID 0000-0002-2985-4099

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this retrospective study was to identify pre-therapeutic predictive laboratory and molecular imaging biomarkers for response and overall survival (OS) in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT). Pre-therapeutic laboratory and [

Indexed as

biomarkermetastatic castration-resistant prostate cancer (mCRPC)PET/CTprostate-specific membrane antigen (PSMA)radioligand therapy (RLT)total lesion PSMA (TLP)

Identifiers

PMID39123398
PMCPMC11311702

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.