Evidence map›Paper›PMID 39123370›Full record

ArticleCancers2024

Uniportal Video-Assisted Thoracoscopic Anatomic Lung Resection after Neoadjuvant Chemotherapy for Lung Cancer: A Case-Matched Analysis.

Marco Andolfi, Elisa Meacci, Michele Salati, Francesco Xiumè, Alberto Roncon, Gian Marco Guiducci, Michela Tiberi, Anna Chiara Nanto, Dania Nachira, Adriana Nocera and 5 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Marco AndolfiDepartment of Thoracic Surgery, AOU delle Marche, 60126 Ancona, Italy.ORCID 0000-0002-0399-7374
Elisa MeacciDepartment of General Thoracic Surgery, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.ORCID 0000-0001-7189-5903
Michele SalatiDepartment of Thoracic Surgery, AOU delle Marche, 60126 Ancona, Italy.
Francesco XiumèDepartment of Thoracic Surgery, AOU delle Marche, 60126 Ancona, Italy.
Alberto RonconDepartment of Thoracic Surgery, AOU delle Marche, 60126 Ancona, Italy.
Gian Marco GuiducciDepartment of Thoracic Surgery, AOU delle Marche, 60126 Ancona, Italy.
Michela TiberiDepartment of Thoracic Surgery, AOU delle Marche, 60126 Ancona, Italy.
Anna Chiara NantoDepartment of Thoracic Surgery, AOU delle Marche, 60126 Ancona, Italy.
Dania NachiraDepartment of General Thoracic Surgery, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.
Adriana NoceraDepartment of General Thoracic Surgery, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.
Giuseppe CalabreseDepartment of General Thoracic Surgery, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.
Maria Teresa CongedoDepartment of General Thoracic Surgery, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.ORCID 0000-0001-5563-0331
Riccardo InchingoloUOC Pneumologia, Dipartimento Neuroscienze, Organi di Senso e Torace, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, 00168 Rome, Italy.ORCID 0000-0003-2843-9966
Stefano MargaritoraDepartment of General Thoracic Surgery, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.
Majed RefaiDepartment of Thoracic Surgery, AOU delle Marche, 60126 Ancona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe advantages of video-assisted thoracic surgery (VATS) are well-recognized in several studies. However, in the cases of advanced lung cancer after neoadjuvant chemotherapy (nCT), the role of VATS is still questionable, with concerns about safety, technical feasibility, and oncological completeness. The aim of this study was to assess the impact of nCT on patients who had undergone uniportal VATS (U-VATS) anatomic lung resections for lung cancer, by comparing the short-term outcomes of patients after nCT with case-matched counterparts (treated by surgery alone).

methodsWe performed a retrospective, comparative study enrolling 927 patients (nCT: 60; non-nCT:867) who underwent U-VATS anatomic lung resections from 2014 to 2020 in two centers. Data were collected in a shared database with standardized variables' definition. Propensity score matching using 15 baseline preoperative patients' characteristics was performed in order to minimize selection-confounding factors between the two groups, which then were directly compared in terms of perioperative outcomes.

resultsAfter propensity score matching, two groups of 60 patients had been defined. The nCT-group had a higher conversion rate compared to the control group (13.3% vs. 0%,

conclusionsU-VATS after nCT is a feasible approach, showing a similar rate of cardiopulmonary complications and length of stay when compared with the control group. However, it remains a challenging surgery due to its great technical complexity as well as the clinical status of the patients.

Indexed as

anatomic lung resectionminimally invasive surgeryneoadjuvant chemotherapyuniportal video-assisted thoracoscopy surgery (VATS)VATS lobectomy

Identifiers

PMID39123370
PMCPMC11311275

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.