Evidence map›Paper›PMID 39123368›Full record

ArticleCancers2024

Acute Pancreatitis in Pediatric Acute Lymphoblastic Leukemia (AcuPA Study): A Nationwide Survey in Poland.

Anna Morawiak, Małgorzata Salamonowicz-Bodzioch, Aleksandra Królak, Krzysztof Kałwak, Joanna Owoc-Lempach, Jerzy Kowalczyk, Joanna Zawitkowska, Tomasz Szczepański, Ninela Irga-Jaworska, Elżbieta Adamkiewicz-Drożyńska and 15 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Anna MorawiakDepartment of Pediatrics, Hemato-Oncology and Gastroenterology, Pomeranian Medical University, Unii Lubelskiej 1, 71-252 Szczecin, Poland.
Małgorzata Salamonowicz-BodziochDepartment of Pediatric, Hematology, Oncology and BMT, Wrocław Medical University, 50-367 Wroclaw, Poland.
Aleksandra KrólakDepartment of Pediatrics, Hemato-Oncology and Gastroenterology, Pomeranian Medical University, Unii Lubelskiej 1, 71-252 Szczecin, Poland.
Krzysztof KałwakDepartment of Pediatric, Hematology, Oncology and BMT, Wrocław Medical University, 50-367 Wroclaw, Poland.
Joanna Owoc-LempachDepartment of Pediatric, Hematology, Oncology and BMT, Wrocław Medical University, 50-367 Wroclaw, Poland.ORCID 0000-0001-7329-4079
Jerzy KowalczykDepartment of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0003-3080-0845
Joanna ZawitkowskaDepartment of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0001-7207-156X
Tomasz SzczepańskiDepartment of Pediatric Hematology and Oncology, Silesian Medical University, 40-055 Zabrze, Poland.ORCID 0000-0001-5336-261X
Ninela Irga-JaworskaDepartment of Pediatrics, Hematology and Oncology, Medical University, 80-210 Gdansk, Poland.
Elżbieta Adamkiewicz-DrożyńskaDepartment of Pediatrics, Hematology and Oncology, Medical University, 80-210 Gdansk, Poland.
Katarzyna AlbrechtDepartment of Pediatric Hematology and Oncology, Medical University, 02-091 Warszawa, Poland.
Anna Szmydki-BaranDepartment of Pediatric Hematology and Oncology, Medical University, 02-091 Warszawa, Poland.
Walentyna BalwierzDepartment of Pediatric Oncology and Hematology, University Children's Hospital, Collegium Medicum Jagiellonian University, 31-008 Krakow, Poland.ORCID 0000-0002-5379-2318
Małgorzata CzogałaDepartment of Pediatric Oncology and Hematology, University Children's Hospital, Collegium Medicum Jagiellonian University, 31-008 Krakow, Poland.ORCID 0000-0003-1277-6810
Jacek WachowiakDepartment of Pediatric Oncology, Hematology and Transplantology, University of Medical Sciences, 61-701 Poznan, Poland.
Katarzyna DerwichDepartment of Pediatric Oncology, Hematology and Transplantology, University of Medical Sciences, 61-701 Poznan, Poland.
Wojciech MłynarskiDepartment of Pediatrics, Hematology and Oncology, Medical University, 90-419 Lodz, Poland.ORCID 0000-0003-2714-5851
Beata Zalewska-SzewczykDepartment of Pediatrics, Hematology and Oncology, Medical University, 90-419 Lodz, Poland.
Maryna Krawczuk-RybakDepartment of Pediatrics, Oncology an Hematology, Medical University, 15-089 Bialystok, Poland.
Małgorzata Sawicka-ŻukowskaDepartment of Pediatrics, Oncology an Hematology, Medical University, 15-089 Bialystok, Poland.ORCID 0000-0002-5463-5656
Jan StyczyńskiDepartment of Pediatrics, Hematology and Oncology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 87-100 Toruń, Poland.ORCID 0000-0002-3158-119X
Andrzej KołtanDepartment of Pediatrics, Hematology and Oncology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 87-100 Toruń, Poland.ORCID 0000-0003-2399-6157
Krzysztof SafranowBiostatistics Teaching Unit, Pomeranian Medical University, 70-204 Szczecin, Poland.ORCID 0000-0001-9415-2758
Tomasz UrasińskiDepartment of Pediatrics, Hemato-Oncology and Gastroenterology, Pomeranian Medical University, Unii Lubelskiej 1, 71-252 Szczecin, Poland.
Tomasz OciepaDepartment of Pediatrics, Hemato-Oncology and Gastroenterology, Pomeranian Medical University, Unii Lubelskiej 1, 71-252 Szczecin, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to identify the risk factors for acute pancreatitis (AP) and its impact on outcomes in Polish children treated for ALL.

methodsThe study group included 2303 children receiving intensive chemotherapy for ALL. The group was divided into patients with at least one episode of AP and those who did not develop AP after treatment for ALL.

resultsThe cumulative incidence of AP in the study group was 4.08%. Older age was an independent risk factor for the development of AP (OR = 1.05; 95%CI = 1.006-1.098;

conclusionsThe incidence of AP in children with ALL is low and related to patients' age. The development of AP does not seem to influence p-DFS and p-EFS in children with ALL. Recurrence of AP after re-exposure to asparaginase in patients with ALL and a history of AP is low (4.5%). Re-exposure to asparaginase after the first episode of AP does not improve either p-DFS or p-EFS in children with ALL.

Indexed as

acute lymphoblastic leukemiaacute pancreatitisasparaginasechildrenintensive chemotherapyrisk factors

Identifiers

PMID39123368
PMCPMC11312082

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.