Evidence map›Paper›PMID 39122904›Full record

ArticleAIDS and behavior2024

Persistent Depression and Suicidal Ideation in People Living with HIV in Tanzania: A Longitudinal Cohort Study.

Megan Willkens, Salama Fadhil, Karl Reis, Matiko Mwita, Grace Ruselu, Bernard Desderius, Godfrey A Kisigo, Robert Peck

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Megan Willkens *Weill Cornell Medicine, Center for Global Health, New York, NY, USA.
Salama Fadhil *Department of Internal Medicine, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
Karl ReisVagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Matiko MwitaDepartment of Psychiatry, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
Grace RuseluDepartment of Internal Medicine, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
Bernard DesderiusDepartment of Internal Medicine, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
Godfrey A KisigoDepartment of Infectious Disease Epidemiology and International Health, London School of Hygiene and Tropical Medicine, London, UK.
Robert PeckWeill Cornell Medicine, Center for Global Health, New York, NY, USA. rnp2002@med.cornell.edu.ORCID http://orcid.org/0000-0002-4526-2480

Funding

HIV, Sleep, Nocturnal Non-dipping, and Cardiovascular Disease: a Tanzanian CohortR01HL160332 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI PECK, ROBERT N · 2021 to 2025
$2.7M
Post-Doctoral Fellowship Training in HIV Clinical InvestigationD43TW011826 · FIC · WEILL MEDICAL COLL OF CORNELL UNIV · PI Daniel W Fitzgerald, Saidi Kapiga · 2021 to 2026
$1.9M
Patient-Oriented Research in Global Cardiovascular Diseases and Interactions with HIVK24HL170902 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Robert N Peck · 2023 to 2026
$504k
FIC NIH HHS D43 TW011826NHLBI NIH HHS K24 HL170902NHLBI NIH HHS NIH R01 HL160322NHLBI NIH HHS R01 HL160332
6 · The paper itself

Abstract

Suicidal ideation and depression are common in people living with HIV (PLWH) in sub-Saharan Africa, but longitudinal data on their persistence in the modern antiretroviral therapy era are lacking. We examined the prevalence of persistent suicidal ideation and depression symptoms using the PHQ-9 in a well-characterized cohort of PLWH and HIV-uninfected community controls. Multivariable logistic regression models were used to determine the relationship between HIV and persistent depression and suicidal ideation. Persistent suicidal ideation was more common in PLWH but there was no difference in persistent depression by HIV status. Approximately one out of five participants with depression at baseline had persistent depression after 12-24 months and only about one out of four participants reporting suicidal ideation at baseline had persistent suicidal ideation after 12-24 months. HIV was associated with suicidal ideation at baseline. Persistent suicidal ideation was significantly associated with HIV immune non-response (p = 0.022). These findings highlight the need for integration of mental health services into HIV care in sub-Saharan Africa with a focus on suicide prevention.

Indexed as

DepressionHIV InfectionsSuicidal IdeationAdultFemaleHumansLogistic ModelsLongitudinal StudiesMaleMiddle AgedPrevalenceRisk FactorsTanzaniaDepressionHIVImmune non-responseSuicidal ideationTanzania

Identifiers

PMID39122904
PMCPMC11825143

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.