Evidence map›Paper›PMID 39122847›Full record

SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2024

Efficacy and safety of laminoplasty combined with C3 laminectomy for patients with multilevel degenerative cervical myelopathy: a systematic review and meta-analysis.

Wenlong Yu, Fan Zhang, Yuanyuan Chen, Xiaoxue Wang, Dingbang Chen, Jianhu Zheng, Xiujie Meng, Quan Huang, Xinghai Yang, Mengchen Yin and 1 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wenlong YuDepartment of Orthopedic, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Fan ZhangDepartment of Orthopedic, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Yuanyuan ChenDepartment of Oncology, Binhu Traditional Chinese Medicine Hospital, Wuxi, 214121, China.
Xiaoxue WangDepartment of Orthopedic, The First Clinical Medical College of Shandong, University of Traditional Chinese Medicine, Jinan, 250000, Shandong, China.
Dingbang ChenDepartment of Orthopedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Jianhu ZhengDepartment of Orthopedic, The First Clinical Medical College of Shandong, University of Traditional Chinese Medicine, Jinan, 250000, Shandong, China.
Xiujie MengDepartment of Orthopedic, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Quan HuangDepartment of Orthopedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Xinghai YangDepartment of Orthopedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China. cnspineyang@163.com.
Mengchen YinDepartment of Orthopedic, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China. yinmengchen0513@126.com.ORCID http://orcid.org/0000-0001-7404-1495
Junming MaDepartment of Orthopedic, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China. junming236@aliyun.com.

Funding

National Natural Science Foundation of China 82205145Project of Chinese Society of Traditional Chinese Medicine youth talent lifting 2023-QNRC2-A03Project of Shanghai Municipal Health Commission 20204Y0165, 20224Y0165Shanghai "Rising Stars of Medical Talents"-Youth Development Program-Youth Medical Talents-Specialist Program SHWSRS 2023-062
6 · The paper itself

Abstract

purposeLaminoplasty (LP) combined with C3 laminectomy (LN) can effectively achieve spinal cord decompression while maintaining the integrity of the posterior ligament-muscle complex, thereby minimizing cervical muscle damage. However, its necessity and safety remain controversial. This study aimed to compare the safety and efficacy of LP and LP combined with C3 LN in the treatment of patients with multilevel degenerative cervical spondylotic myelopathy (DCM).

methodsA systematic review and meta-analysis of the literature was performed. A search of PubMed, Web of Science, Embase, and the Cochrane Library databases was conducted from inception through December 2023 and updated in February 2024. Search terms included laminoplasty, laminectomy, C3 and degenerative cervical spondylosis. The literature search yielded 14 studies that met our inclusion criteria. Outcomes included radiographic results, neck pain, neurologic function, surgical parameters, and postoperative complications. We also assessed methodologic quality, publication bias, and quality of evidence.

resultsFourteen studies were identified, including 590 patients who underwent LP combined with C3 LN (modified group, MG) compared to 669 patients who underwent LP (traditional group, TG). The results of the study indicated a statistically significant improvement in cervical range of motion (WMD = 3.62, 95% CI: 0.39 to 6.85) and cervical sagittal angle (WMD = 2.07, 95% CI: 0.40 to 3.74) in the MG compared to the TG at the last follow-up (very low-level evidence). The TG had a higher number of patients with complications, especially C2-3 bone fusion. There was no significant difference found in improvement of neck pain, JOA, NDI, cSVA, T1 slope at latest follow-up.

conclusionLP combined with C3 LN is an effective and necessary surgical method for multilevel DCM patients to maintain cervical sagittal balance. However, due to the low quality of evidence in existing studies, more and higher quality research on the technology is needed in the future.

Indexed as

Cervical VertebraeLaminectomyLaminoplastySpinal Cord DiseasesSpondylosisDecompression, SurgicalHumansTreatment OutcomeC3Degenerative cervical myelopathyLaminectomyLaminoplastyMeta-analysis

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.