ArticleNature aging2024
Real-life intrinsic capacity screening data from the ICOPE-Care program.
Article in Nature aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Trial
- Impact of a nurse-led multidomain intervention on intrinsic capacity among community-dwelling older adults in China: a cluster randomized trial.BMC public health · 2025Trial
- Intrinsic capacity and mortality in community-dwelling octogenarians: a network analysis from the ilSIRENTE study.GeroScience · 2026Article
- AI-Based Measurement Tools for Intrinsic Capacity in Older Adults: Scoping Review.Journal of medical Internet research · 2026Article
- Intrinsic capacity subtypes in healthy Chinese older adults: links to possible sarcopenia and fall risk.The journal of nutrition, health & aging · 2026Article
- Mapping the impact of intrinsic capacity on healthcare use.The journal of nutrition, health & aging · 2026Article
- Associations between intrinsic capacity, subjectively perceived environmental support and functional status among rural disabled older adults in China: guided by the healthy ageing framework.BMC public health · 2026Article
- Healthy longevity, intrinsic capacity, geroscience and Alzheimer's disease prevention.The journal of prevention of Alzheimer's disease · 2026Article
- Socioeconomic status and intrinsic capacity trajectories among middle-aged and older adults in China: mediating role of cognitive leisure activities.The journal of nutrition, health & aging · 2026Article
- Could animal models be used to longitudinally track intrinsic capacity during aging?The journal of nutrition, health & aging · 2026Article
- Implementing a nationwide healthy longevity program for older adults.Nature aging · 2026Article
- Inflammatory score, intrinsic capacity and the risk of new-onset chronic lung disease: a cohort study from the China Health and Retirement Longitudinal Study.Journal of thoracic disease · 2026Article
- Hearing loss associated with mobility and cognitive impairment: comorbid condition, an intrinsic capacity-aligned vulnerability cluster or a syndromic clustering?The journal of nutrition, health & aging · 2026Article
- A decade of difference: cross-continental patterns of functional performance in Brazil and Europe within the WHO ICOPE framework.PloS one · 2026Observational
- Article
- Development and Validation of the Healthy Longevity Index for Personalized Healthy Aging in Primary Care: Cross-National Retrospective Analysis.JMIR aging · 2025Article
- A genome-wide association study identified 10 novel genomic loci associated with intrinsic capacity.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Article
- Association of intrinsic capacity with leisure activities in community-dwelling older adults: a cross-sectional analysis.BMC geriatrics · 2025Article
- Associations of the Neutrophil-to-Lymphocyte Ratio(NLR), Triglyceride-Glucose Index (TyG), and TyG-derived indices with vitality decline in older adults in China: a study within the Integrated Care for Older People (ICOPE) framework.Lipids in health and disease · 2025Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
The Integrated Care for Older People (ICOPE) program is a healthcare pathway that uses a screening test for intrinsic capacity (IC) as its entry point. However, real-life data informing on how IC domains cluster and change over time, as well as their clinical utility, are lacking. Using primary healthcare screening data from more than 20,000 French adults 60 years of age or older, this study identified four clusters of IC impairment: 'Low impairment' (most prevalent), 'Cognition+Locomotion+Hearing+Vision', 'All IC impaired' and 'Psychology+Vitality+Vision'. Compared to individuals with 'Low impairment', those in the other clusters had higher likelihood of having frailty and limitations in both activities of daily living (ADL) and instrumental activities of daily living (IADL), with the strongest associations being observed for 'All IC impaired'. This study found that ICOPE screening might be a useful tool for patient risk stratification in clinical practice, with a higher number of IC domains impaired at screening indicating a higher probability of functional decline.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.