Evidence map›Paper›PMID 39122776›Full record

ArticleScientific reports2024

Characterizing bone density pattern and porosity in the human ossicular chain using synchrotron microtomography.

Aleksandra Ivanovic, Fabian Schalbetter, Margaux Schmeltz, Wilhelm Wimmer, Marco Caversaccio, Marco Stampanoni, Anne Bonnin, Lukas Anschuetz

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The Retrotympanum Revisited By a Volumetric Approach Using Synchrotron-Based X-Ray Phase-Contrast Imaging.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026
    Article
  2. The crossroads between osteosarcopenia and intrinsic capacity-a narrative review.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aleksandra IvanovicDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, Universityof Bern, Bern, Switzerland. aleksandra.ivanovic@unibe.ch.
Fabian SchalbetterDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, Universityof Bern, Bern, Switzerland.
Margaux SchmeltzPaul Scherrer Institut, Swiss Light Source, Villigen PSI, Villigen, Switzerland.
Wilhelm WimmerDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, Universityof Bern, Bern, Switzerland.
Marco CaversaccioDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, Universityof Bern, Bern, Switzerland.
Marco StampanoniPaul Scherrer Institut, Swiss Light Source, Villigen PSI, Villigen, Switzerland.
Anne BonninPaul Scherrer Institut, Swiss Light Source, Villigen PSI, Villigen, Switzerland.
Lukas AnschuetzDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, Universityof Bern, Bern, Switzerland.

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 320030\_192660
6 · The paper itself

Abstract

The auditory ossicles amplify and transmit sound from the environment to the inner ear. The distribution of bone mineral density is crucial for the proper functioning of sound transmission as the ossicles are suspended in an air-filled chamber. However, little is known about the distribution of bone mineral density along the human ossicular chain and within individual ossicles. To investigate this, we analyzed fresh-frozen human specimens using synchrotron-based phase-contrast microtomography. In addition, we analyzed the volume and porosity of the ossicles. The porosity for the auditory ossicles lies, on average, between 1.92% and 9.85%. The average volume for the mallei is 13.85 ± 2.15 mm

Indexed as

Bone DensityEar OssiclesSynchrotronsX-Ray MicrotomographyAgedFemaleHumansMaleMiddle AgedPorosityStapes

Identifiers

PMID39122776
PMCPMC11315917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.