Evidence map›Paper›PMID 39122482›Full record

ArticleMacromolecular rapid communications2024

Density-Nematic Coupling in Isotropic Solution of DNA: Multiscale Model.

Daniel Svenšek, Jaka Sočan, Matej Praprotnik

Erratum issuedAbstract read
In one paragraph

Article in Macromolecular rapid communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Daniel SvenšekLaboratory for Molecular Modeling, National Institute of Chemistry, Ljubljana, SI-1001, Slovenia.
Jaka SočanLaboratory for Molecular Modeling, National Institute of Chemistry, Ljubljana, SI-1001, Slovenia.
Matej PraprotnikLaboratory for Molecular Modeling, National Institute of Chemistry, Ljubljana, SI-1001, Slovenia.

Funding

Javna Agencija za Raziskovalno Dejavnost RS J1-3027Javna Agencija za Raziskovalno Dejavnost RS J4-3087Javna Agencija za Raziskovalno Dejavnost RS P1-0002
6 · The paper itself

Abstract

Monte Carlo simulations of isotropic solutions of double-stranded DNA (deoxyribonucleic acid) are performed using the well-established oxDNA model. By comparing the fluctuation amplitudes with theoretical predictions, the parameters of a generic macroscopic model of an isotropic linear polymer solution/melt are determined. A multiscale continuum field model is thus obtained, corresponding to the full specificity of the isotropic phase of double-stranded DNA in the usual B-form as perceived at the macroscopic level. Present research is particularly focused on the coupling between spatial concentration/density variations of the polymer and the emerging nematic orientation order of the chains. This rather unfamiliar, only recently described phenomenon, inherent to linear polymers, is outlined and interpreted. Quantitative predictions are provided for the degree of nematic order induced by concentration gradients in isotropic solutions of double-stranded DNA.

Indexed as

DNAMonte Carlo MethodSolutionsNucleic Acid ConformationDNASolutionsdensity–nematic couplingDNAisotropic phaselinear polymers

Identifiers

PMID39122482
PMCPMC11661675

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.