Evidence map›Paper›PMID 39121211›Full record

ArticleScience advances2024

Magnesium induced structural reorganization in the active site of adenylate kinase.

Kwangho Nam, Abdul Raafik Arattu Thodika, Sonja Tischlik, Chanrith Phoeurk, Tamás Milán Nagy, Léon Schierholz, Jörgen Ådén, Per Rogne, Malte Drescher, A Elisabeth Sauer-Eriksson and 1 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Transient ion-mediated interactions regulate subunit rotation in a eukaryotic ribosome.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Copper-Induced Stimulation of Ectophosphatase Activity ofPathogens (Basel, Switzerland) · 2025
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kwangho NamDepartment of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, TX 76019, USA.ORCID 0000-0003-0723-7839
Abdul Raafik Arattu ThodikaDepartment of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, TX 76019, USA.ORCID 0009-0001-4973-5265
Sonja TischlikDepartment of Chemistry, Konstanz Research School Chemical Biology, University of Konstanz, 78464 Konstanz, Germany.ORCID 0000-0001-7518-2441
Chanrith PhoeurkDepartment of Chemistry, Umeå University, 901 87 Umeå, Sweden.ORCID 0000-0002-8025-4232
Tamás Milán NagyDepartment of Chemistry, Umeå University, 901 87 Umeå, Sweden.ORCID 0000-0003-4766-1992
Léon SchierholzDepartment of Chemistry, Umeå University, 901 87 Umeå, Sweden.
Jörgen ÅdénDepartment of Chemistry, Umeå University, 901 87 Umeå, Sweden.ORCID 0000-0002-4480-1219
Per RogneDepartment of Chemistry, Umeå University, 901 87 Umeå, Sweden.ORCID 0000-0002-3687-9200
Malte DrescherDepartment of Chemistry, Konstanz Research School Chemical Biology, University of Konstanz, 78464 Konstanz, Germany.ORCID 0000-0002-3571-3452
A Elisabeth Sauer-ErikssonDepartment of Chemistry, Umeå University, 901 87 Umeå, Sweden.ORCID 0000-0003-0124-0199
Magnus Wolf-WatzDepartment of Chemistry, Umeå University, 901 87 Umeå, Sweden.ORCID 0000-0002-9098-7974

Funding

Multiscale Modeling of Protein Kinase Structure, Catalysis and AllosteryR01GM132481 · NIGMS · UNIVERSITY OF TEXAS ARLINGTON · PI Kwangho Nam · 2019 to 2026
$1.7M
NIGMS NIH HHS R01 GM132481
6 · The paper itself

Abstract

Phosphoryl transfer is a fundamental reaction in cellular signaling and metabolism that requires Mg

Indexed as

Adenylate KinaseCatalytic DomainMagnesiumMolecular Dynamics SimulationAdenosine DiphosphateAdenosine TriphosphateProtein ConformationAdenosine DiphosphateAdenosine TriphosphateAdenylate KinaseMagnesium

Identifiers

PMID39121211
PMCPMC11313852

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.