Evidence map›Paper›PMID 39120859›Full record

ReviewUpdates in surgery2025

Advocating for a "shift-to-left" in transplant oncology: left grafts, RAPID and dual graft.

Umberto Cillo, Alessandro Furlanetto, Enrico Gringeri, Alessandra Bertacco, Andrea Marchini, Eugenia Rosso, Domenico Bassi, Francesco Enrico D'Amico, Pal Dag Line

Abstract readReview
PubMed Publisher
In one paragraph

Review in Updates in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Present and future of liver transplantation for cholangiocellular carcinoma: moving toward personalized multiparametric transplantability patterns.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Umberto Cillo *Hepato-Biliary-Pancreatic Surgery and Liver Transplantation Unit, Chirurgia Generale 2, Padua University Hospital, Via N. Giustiniani 2, 35128, Padua, Italy. cillo@unipd.it.ORCID http://orcid.org/0000-0002-2310-0245
Alessandro Furlanetto *Hepato-Biliary-Pancreatic Surgery and Liver Transplantation Unit, Chirurgia Generale 2, Padua University Hospital, Via N. Giustiniani 2, 35128, Padua, Italy.
Enrico GringeriHepato-Biliary-Pancreatic Surgery and Liver Transplantation Unit, Chirurgia Generale 2, Padua University Hospital, Via N. Giustiniani 2, 35128, Padua, Italy.
Alessandra BertaccoHepato-Biliary-Pancreatic Surgery and Liver Transplantation Unit, Chirurgia Generale 2, Padua University Hospital, Via N. Giustiniani 2, 35128, Padua, Italy.
Andrea MarchiniHepato-Biliary-Pancreatic Surgery and Liver Transplantation Unit, Chirurgia Generale 2, Padua University Hospital, Via N. Giustiniani 2, 35128, Padua, Italy.
Eugenia RossoHepato-Biliary-Pancreatic Surgery and Liver Transplantation Unit, Chirurgia Generale 2, Padua University Hospital, Via N. Giustiniani 2, 35128, Padua, Italy.
Domenico BassiHepato-Biliary-Pancreatic Surgery and Liver Transplantation Unit, Chirurgia Generale 2, Padua University Hospital, Via N. Giustiniani 2, 35128, Padua, Italy.
Francesco Enrico D'AmicoHepato-Biliary-Pancreatic Surgery and Liver Transplantation Unit, Chirurgia Generale 2, Padua University Hospital, Via N. Giustiniani 2, 35128, Padua, Italy.
Pal Dag LineDepartment of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The extension of liver transplantation to new oncologic indications might exacerbate the shortage of grafts. Living donor liver transplantation (LDLT) may emerge as a viable resource, although its diffusion in the Western world is still very limited. Several groups have advocated for minimizing the impact on donors by reducing the extent of donor hepatectomy, i.e., shifting from right-lobe to left-lobe or left-lateral segment donation ("shift-to-left"). This is particularly relevant when dealing with non-established indications and could make it more acceptable both for potential donors and for the recipients. Left grafts can be transplanted straightforward, despite a higher risk of small-for-size syndrome, or they can be used in the setting of dual-graft LDLT or RAPID procedures, despite technical complexity. This review will expose the most relevant features of each technique, highlighting their strengths and pitfalls and focusing on outcomes. This wide set of tools should be available at high-volume transplant centers, to propose the best technique to adapt to donor-recipient matching.

Indexed as

HepatectomyLiver NeoplasmsLiver TransplantationLiving DonorsHumansDual graftLDLTLiver transplantationLiving donorRAPID

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.