Evidence map›Paper›PMID 39120788›Full record

ArticlePharmaceutical medicine2024

P.O.L.A.R. Star: A New Framework Developed and Applied by One Mid-Sized Pharmaceutical Company to Drive Digital Transformation in R&D.

Riccardo Mariani, Maria Carmela De Vuono, Elena Businaro, Silvia Ivaldi, Tina Dell'Armi, Michele Gallo, Diego Ardigò

Abstract read
In one paragraph

Article in Pharmaceutical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Riccardo MarianiChiesi Farmaceutici Spa, Largo Francesco Belloli 11/A, 43122, Parma, Italy. r.mariani@chiesi.com.ORCID 0009-0004-9727-1647
Maria Carmela De VuonoChiesi Farmaceutici Spa, Largo Francesco Belloli 11/A, 43122, Parma, Italy.
Elena BusinaroChiesi Farmaceutici Spa, Largo Francesco Belloli 11/A, 43122, Parma, Italy.
Silvia IvaldiChiesi Farmaceutici Spa, Largo Francesco Belloli 11/A, 43122, Parma, Italy.
Tina Dell'ArmiEVERSANA INTOUCH Healthware, Salerno, Italy.
Michele GalloEVERSANA INTOUCH Healthware, Salerno, Italy.
Diego ArdigòChiesi Farmaceutici Spa, Largo Francesco Belloli 11/A, 43122, Parma, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Digital transformation has become a cornerstone of innovation in pharmaceutical research and development (R&D). Pharmaceutical companies now have an imperative to embrace transformation, including mid-sized and small-sized companies despite resource limitations that do not allow economies of scale compared with larger organizations. This article describes the journey undertaken by Chiesi to develop an efficient framework to drive digital transformation along its R&D value chain with the objective of building and refreshing a clear roadmap and relevant priorities, together with identifying and enabling new digital capabilities and skills within R&D, defining tools and processes that will guide Chiesi activities in the space up to mid-long term. This work has led so far to five main achievements, which align with the steps in the framework: a strategically aligned roadmap with key focus areas for digital transformation and a dedicated team to lead the effort; a common language for data across the R&D value chain; an internal mindset that's open to innovation and participation in key external networks and consortia; a set of quick-win use cases for the new framework; and a defined set of Key Performance Indicators (KPIs) and monitoring tools for digital transformation. The work presented here demonstrates that R&D digital transformation should represent an ongoing process to enable cross-functional collaboration and integration within complex corporate environments that face an ever-growing volume of diverse data, to efficiently support business needs, and to ensure a positive impact on patient care.

Indexed as

Drug IndustryHumansPharmaceutical ResearchResearch

Identifiers

PMID39120788
PMCPMC11473631

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.