Evidence map›Paper›PMID 39120594›Full record

ReviewJournal of cell science2024

Actin network evolution as a key driver of eukaryotic diversification.

Katrina B Velle, Andrew J M Swafford, Ethan Garner, Lillian K Fritz-Laylin

Abstract readReview
In one paragraph

Review in Journal of cell science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. The Role of Arp2/3 in End-Resection During DNA Double-Strand Break Repair.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  2. TheMolecular biology of the cell · 2026
    Article
  3. Article
  4. Article
  5. ThebioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katrina B VelleDepartment of Biology, University of Massachusetts Dartmouth, Dartmouth, MA 02747, USA.ORCID 0000-0002-9985-9522
Andrew J M SwaffordDepartment of Biology, Middlebury College, Middlebury, VT 05753, USA.ORCID 0000-0001-7687-9662
Ethan GarnerDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.
Lillian K Fritz-LaylinDepartment of Biology, University of Massachusetts Amherst, Amherst, MA 01003, USA.ORCID 0000-0002-9237-9403

Funding

Chytrid fungi and the functional specification of actin networksR35GM143039 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI FRITZ-LAYLIN, LILLIAN KATHLEEN · 2021 to 2025
$1.9M
Canadian Institute for Advanced ResearchNIGMS NIH HHS R35 GM143039University of Massachusetts Amherst
6 · The paper itself

Abstract

Eukaryotic cells have been evolving for billions of years, giving rise to wildly diverse cell forms and functions. Despite their variability, all eukaryotic cells share key hallmarks, including membrane-bound organelles, heavily regulated cytoskeletal networks and complex signaling cascades. Because the actin cytoskeleton interfaces with each of these features, understanding how it evolved and diversified across eukaryotic phyla is essential to understanding the evolution and diversification of eukaryotic cells themselves. Here, we discuss what we know about the origin and diversity of actin networks in terms of their compositions, structures and regulation, and how actin evolution contributes to the diversity of eukaryotic form and function.

Indexed as

Actin CytoskeletonActinsEukaryotic CellsAnimalsBiological EvolutionEukaryotaEvolution, MolecularHumansSignal TransductionActinsActinCytoskeletonEvolution

Identifiers

PMID39120594
PMCPMC12050087

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.