ArticleHealthcare (Basel, Switzerland)2024
Diagnostic Values of Serum Inflammatory Biomarkers after Hip and Knee Arthroplasty in Patients with Periprosthetic Joint Infection.
Article in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Key Inflammatory Pathways, Biomarkers, and Targeted Management Strategies in Primary Total Joint Arthroplasty: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Inflammatory Biomarkers Following Orthopedic Surgery: Current Evidence, Clinical Applications, and Future Perspectives-A Narrative Review.Journal of clinical medicine · 2026Review
- Intraoperative Contamination of Sterile Fields and Postoperative Implications in Total Hip and Knee Arthroplasty: A Prospective Observational Study.Journal of clinical medicine · 2026Article
- Continuous monitoring of serum markers for early detection of periprosthetic joint infection in osteoporotic patients undergoing hip arthroplasty: A prospective cohort study.Journal of medical biochemistry · 2026Article
- Key factors influencing orthopaedic operating room contamination: Impact of human activity andJournal of experimental orthopaedics · 2025Article
- Challenges and Complications in Treating Total Knee Arthroplasty in Morbidly Obese Patients.Cureus · 2024Article
- Advances and Challenges in Orthopedic Implant-Associated Infections.Healthcare (Basel, Switzerland) · 2024Article
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Authors and funding
7 authors.
Funding
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Abstract
One of the complications after total hip arthroplasty (THA) or total knee arthroplasty (TKA) is periprosthetic joint infection (PJI). Numerous studies have been performed to explore the value of biological parameters in the early identification of infection rates after THA and TKA. This study investigates alterations in inflammatory markers associated with PJI. This retrospective study focused on a cohort of patients with hip and knee arthroplasty treated between 2016 and 2022. CRP, ESR, and fibrinogen were observed preoperatively, on days one, three, six, and twenty-one postoperatively. From a total of 4076 THA and TKA performed during this period, 62 patients were identified with periprosthetic infections. We also identified the pathogens responsible for infections in order to assess if asymptomatic preoperative infections were involved in PJI. In patients with acute infections following TKA, days one and three postoperative recorded a CRP value below the expected range. The value of CRP in patients with early infection after THA was significantly increased on day six postoperative. ESR and fibrinogen values were not statistically significantly correlated with early PJI. The CRP level in acute PJI shows different patterns than those shown in the literature.
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