Evidence map›Paper›PMID 39119984›Full record

ArticleJournal of the American Heart Association2024

Impact of Chronic Kidney Disease on the Processes of Care and Long-Term Mortality of Non-ST-Segment-Elevation Myocardial Infarction: A Nationwide Cohort Study and Long-Term Follow-Up.

Nicholas Weight, Saadiq Moledina, Mohsin Ullah, Harindra C Wijeysundera, Simon Davies, Nicholas W S Chew, Claire Lawson, Safi U Khan, Chris P Gale, Muhammad Rashid and 1 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Sex differences in survival following acute coronary syndrome with and without standard modifiable risk factors.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Pooled it
  2. Article
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  6. Review
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  9. Impact of Heart Failure and Chronic Kidney Disease on All-Cause Mortality in Patients Undergoing Coronary Angiography: Results From the Finnish Kardio Multicentre Registry.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nicholas WeightKeele Cardiovascular Research Group, Centre for Prognosis Research Institute for Primary Care and Health Sciences, Keele University Keele Staffordshire United Kingdom.ORCID 0000-0001-5952-7542
Saadiq MoledinaKeele Cardiovascular Research Group, Centre for Prognosis Research Institute for Primary Care and Health Sciences, Keele University Keele Staffordshire United Kingdom.
Mohsin UllahKeele Cardiovascular Research Group, Centre for Prognosis Research Institute for Primary Care and Health Sciences, Keele University Keele Staffordshire United Kingdom.ORCID 0000-0001-6094-380X
Harindra C WijeysunderaSchulich Heart Program, Sunnybrook Health Sciences Centre University of Toronto, ICES Toronto Toronto Canada.ORCID 0000-0001-8464-1080
Simon DaviesDepartment of Renal Medicine, School of Medicine Keele University Keele Staffordshire United Kingdom.ORCID 0000-0001-5127-4755
Nicholas W S ChewDepartment of Cardiology, National University Heart Centre National University Health System Singapore.ORCID 0000-0002-0640-0430
Claire LawsonDepartment of Cardiovascular Sciences University of Leicester United Kingdom.ORCID 0000-0003-0127-5236
Safi U KhanDepartment of Cardiology Houston Methodist DeBakey Heart and Vascular Center Houston Texas USA.ORCID 0000-0003-1559-6911
Chris P GaleLeeds Institute for Cardiovascular and Metabolic Medicine University of Leeds United Kingdom.ORCID 0000-0003-4732-382X
Muhammad RashidKeele Cardiovascular Research Group, Centre for Prognosis Research Institute for Primary Care and Health Sciences, Keele University Keele Staffordshire United Kingdom.ORCID 0000-0001-9725-1583
Mamas A MamasKeele Cardiovascular Research Group, Centre for Prognosis Research Institute for Primary Care and Health Sciences, Keele University Keele Staffordshire United Kingdom.ORCID 0000-0001-9241-8890

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA growing population of patients with chronic kidney disease (CKD) presents with non-ST-segment-elevation myocardial infarction, although little is known about their longer-term mortality. METHODS AND

resultsUsing the MINAP (Myocardial Ischaemia National Audit Project) registry, linked to Office for National Statistics mortality data, we analyzed 363 559 UK patients with non-ST-segment-elevation myocardial infarction, with or without CKD. Cox regression models were fitted, adjusting for baseline demographics. Compared with patients without CKD, patients with CKD were less frequently prescribed P2Y12 inhibitors (89% versus 86%,

conclusionsPatients with CKD were significantly less likely to receive invasive investigation or undergo percutaneous coronary intervention and had significantly higher risk of short- and longer-term mortality. Risk of mortality increased with reducing CKD stage. Cardiovascular disease was the main cause of mortality in patients with CKD, but at comparable rates to the general population with non-ST-segment-elevation myocardial infarction.

Indexed as

Non-ST Elevated Myocardial InfarctionRegistriesRenal Insufficiency, ChronicAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedOutcome and Process Assessment, Health CarePercutaneous Coronary InterventionRisk AssessmentRisk FactorsTime FactorsUnited Kingdomchronic kidney diseasenon–ST‐segment–elevation myocardial infarctionquality of care

Identifiers

PMID39119984
PMCPMC11963930

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.