Evidence map›Paper›PMID 39119972›Full record

ArticleJournal of the American Heart Association2024

Safety of Antiplatelet Therapy in Noncardioembolic Ischemic Stroke With Thrombocytopenia: The CASE II Study.

Dongjuan Xu, Huan Zhou, Tingxia Zhang, Weiwei Gong, Jieming Zhong, Han Yu, Fujian Chen, Wansi Zhong, Shenqiang Yan, Min Lou and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dongjuan XuDepartment of Neurology Dongyang Affiliated Hospital of Wenzhou Medical University Dongyang China.
Huan ZhouDepartment of Neurology The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou China.
Tingxia ZhangDepartment of Neurology The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou China.
Weiwei GongZhejiang Provincial Center for Disease Control and Prevention Hangzhou China.
Jieming ZhongZhejiang Provincial Center for Disease Control and Prevention Hangzhou China.
Han YuDepartment of Neurology Yongjia people's Hospital Yongjia China.
Fujian ChenDepartment of Neurology People's Hospital of Anji Anji China.
Wansi ZhongDepartment of Neurology The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou China.
Shenqiang YanDepartment of Neurology The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou China.ORCID 0000-0001-6425-0672
Min LouDepartment of Neurology The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou China.ORCID 0000-0002-6627-064X
CASE II investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is scant evidence regarding the safety of antiplatelet therapy in acute ischemic stroke (AIS) patients with thrombocytopenia. Our study aims to address this concern by examining AIS patients with thrombocytopenia from a large database in real-world settings. METHODS AND

resultsWe included patients with AIS with a platelet count <100×10

conclusionsThe use of antiplatelet therapy lessened as platelet count decreased in patients with AIS with thrombocytopenia. However, our findings suggest that antiplatelet medications remain safe and effective for this population.

Indexed as

Ischemic StrokePlatelet Aggregation InhibitorsThrombocytopeniaAgedAged, 80 and overFemaleFunctional StatusHumansMaleMiddle AgedPlatelet CountPropensity ScoreRegistriesRisk FactorsTime FactorsTreatment OutcomePlatelet Aggregation Inhibitorsantiplateletbleeding eventischemic strokereal‐world studythrombocytopenia

Identifiers

PMID39119972
PMCPMC11963942

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.