ArticleIndian journal of dermatology
Impact of Chemotherapy-Induced Nail Changes on Quality of Life: A Cross-Sectional Study from a Tertiary Care Centre.
Article in Indian journal of dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Corrective and Restorative Dermatology in Cancer Survivors: An Urgent Unmet Need!American journal of clinical dermatology · 2026Review
- The cutaneous mirror: leveraging drug-induced skin phenotypes as early visual risk signals for systemic toxicity, a comprehensive review.Frontiers in drug safety and regulation · 2026Review
- Multidisciplinary Management of Severe Taxane-Induced Nail Toxicity in a Breast Cancer Patient.Cancer management and research · 2026Article
- Impact of Plastic Surgery of Nail Folds Combined with Conservative Nail Plate Reconstruction on the Quality of Life in Patients with Ingrown Toenails: A DLQI-Based Study.Journal of clinical medicine · 2025Article
- Aesthetic satisfaction of patients following plastic surgery of nail folds combined with conservative nail plate reconstruction for ingrown toenails.Frontiers in medicine · 2025Article
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Authors and funding
4 authors.
Funding
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Abstract
Background: Chemotherapy has increased survival rate in patients but is associated with systemic as well as cutaneous adverse effects. Among cutaneous adverse effects, nail changes caused by chemotherapy are often overlooked. But these changes are a major cause of cosmetic concern and negatively affect the quality of life (QoL) of patients. Aim: This study was conducted to evaluate the impact of chemotherapy-induced nail changes on QoL of patients with malignancy and to compare the severity of impact on QoL in various nail changes. Materials and Methods: This hospital-based cross-sectional observational study was conducted for a period of 12 months. Only patients on chemotherapy who developed nail changes were included in the study. A nail-specific QoL questionnaire was used. Statistical analysis was conducted to evaluate the impact of nail changes on QoL. Results: The mean QoL score of 188 patients was 32.37 ± 7.9. The mean QoL score of females was more than that of males. QoL was statistically more significant in younger age groups [<20 years: 46.71 ± 1.7] ( Conclusion: There is a significant impact of chemotherapy-induced nail changes on QoL of patients leading to psychological distress, reduced self-confidence and social limitation. This highlights the importance of proper counselling of patients beforehand regarding the possibility of associated nail changes during and after the chemotherapy regimens.
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