ArticleGenetics in medicine open2024
Blind to the perils of pursuing food: Behaviors of individuals with Smith-Magenis Syndrome.
Article in Genetics in medicine open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed.
- Tirzepatide for weight and behavior management in a patient with Smith-Magenis syndrome.JCEM case reports · 2026Article
- From Behavioral and Sleep Disturbances to Genetic Diagnosis: Smith-Magenis Syndrome and the Importance of the Diagnostic Pathway.Developmental neurobiology · 2026Article
- Weight Loss Following Liraglutide Therapy in a Patient With Smith-Magenis Syndrome: A Case Report.Cureus · 2026Article
- Empowering through structured boundaries: an integral model for fostering balanced eating and nutritional well-being.Journal of rare diseases (Berlin, Germany) · 2026Article
- Investigating food-related behaviors in Smith-Magenis syndrome: tailoring a questionnaire for a rare disease.Journal of rare diseases (Berlin, Germany) · 2026Article
- Weight Management in a Patient With Smith-Magenis Syndrome: The Role of GLP-1 Receptor Agonists.JCEM case reports · 2025Article
- Investigation of setmelanotide, an MC4R agonist, for obesity in individuals with Smith-Magenis syndrome.Obesity research & clinical practiceArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Purpose: Discrepancies exist between the need to lock food away and satiety scores in the Smith-Magenis syndrome (SMS) population. This study sought to uncover food-related behaviors within this unique group of individuals. Methods: Caregivers ( Results: This study identified a global theme of "Blind to the perils while pursuing their goals," supported by 5 organizing themes: (1) Biology-impacting behaviors, (2) Need for personalized strategies, (3) Controlling food experiences, (4) Need for parents to orchestrate life, and (5) Surprising resourcefulness. Subthemes within these organizing themes highlighted that individuals with SMS have unique food-related behaviors and often fixate on certain types of foods. Their constant obsession with food for many of them is driven by hunger, obsessive characteristics, a need for autonomy, and a need for fairness. Caregivers must put multiple guardrails in place and remain constantly vigilant to prevent overeating in these individuals. Conclusion: Individuals with SMS often perseverate on food and display unique food-related behaviors. Treating obesity in this population is likely to be ineffective without multicomponent, individualized strategies. Additionally, research in this population will likely require targeted instruments for the SMS population to more clearly define the underlying etiologies and to track changes over time in therapeutic trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.