Evidence map›Paper›PMID 39118900›Full record

ReviewJournal of maxillofacial and oral surgery2024

Nano-Drug Carriers for Targeted Therapeutic Approaches in Oral Cancer: A Systematic Review.

Vivekanand Kattimani, Nom Kumar Naik Bhukya, Gnana Sarita Kumari Panga, Abhisikta Chakrabarty, Prasanth Lingamaneni

Abstract readReview
In one paragraph

Review in Journal of maxillofacial and oral surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vivekanand KattimaniSIBAR Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh 522509 India.ORCID 0000-0002-9812-7207
Nom Kumar Naik BhukyaDepartment of Anatomy, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka 576104 India.ORCID 0000-0002-5643-6802
Gnana Sarita Kumari PangaSIBAR Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh 522509 India.ORCID 0000-0003-4024-9006
Abhisikta ChakrabartyDepartment of Oral and Maxillofacial Pathology, GDCRI, Bangalore, India.ORCID 0000-0002-5409-4247
Prasanth LingamaneniDivision of Medical Oncology, Mayo Clinic, Rochester, MN USA.ORCID 0000-0003-2575-1823

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Nanotechnology has shown potential in treating different types of cancers. In particular, nano-drug delivery systems (DDSs) offer a promising strategy for treating oral cancer. By customizing therapy and improving drug delivery, these systems can improve outcomes for patients. Hence, a review was conducted to assess the current evidence and explore the use of DDSs for treating oral cancer. Aim: To comprehensively explore the nano-drug carriers and target delivery for oral cancer therapy and to discuss the benefits, challenges, and potential to guide future research and clinical practice. Methodology: A systematic search of articles archived in PubMed, Scopus, and Cochrane using keywords such as Nano, drug carrier, target drug delivery, and oral cancer was performed to fulfill the objectives from inception till February 2, 2024. Articles providing insights into nano-drug carriers in oral cancer were included. Results: The results revealed a total of 156 articles. After duplicate removal, 136 articles were screened for title and abstract as per the inclusion and exclusion criteria. A total of 113 articles were excluded with reasons. Out of the remaining 23 articles, only 11 were included for qualitative data synthesis. Conclusion: The literature revealed scarcity of oral cancer-related work using DDSs. Qualitative synthesis of data revealed that nano-drug carriers demonstrated a promising avenue for targeted therapeutic approaches in oral cancer, despite the challenges and their potential benefits. Continued research and development in this field are crucial to overcoming these challenges and fully realizing the potential of nano-drug carriers in revolutionizing oral cancer therapy. Supplementary Information: The online version contains supplementary material available at 10.1007/s12663-024-02251-z.

Indexed as

ChemotherapyDrug deliveryManagementNanotechnologyTumor

Identifiers

PMID39118900
PMCPMC11303611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.