Evidence map›Paper›PMID 39118603›Full record

ArticleChemical science2024

Lewis acid-catalyzed diastereoselective formal ene reaction of thioindolinones/thiolactams with bicyclobutanes.

Avishek Guin, Shiksha Deswal, Mahesh Singh Harariya, Akkattu T Biju

Abstract read
In one paragraph

Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Avishek GuinDepartment of Organic Chemistry, Indian Institute of Science Bangalore 560012 India avishekguin@iisc.ac.in atbiju@iisc.ac.in https://atbiju.in/.ORCID https://orcid.org/0000-0003-3421-6910
Shiksha DeswalDepartment of Organic Chemistry, Indian Institute of Science Bangalore 560012 India avishekguin@iisc.ac.in atbiju@iisc.ac.in https://atbiju.in/.
Mahesh Singh HarariyaDepartment of Organic Chemistry, Indian Institute of Science Bangalore 560012 India avishekguin@iisc.ac.in atbiju@iisc.ac.in https://atbiju.in/.
Akkattu T BijuDepartment of Organic Chemistry, Indian Institute of Science Bangalore 560012 India avishekguin@iisc.ac.in atbiju@iisc.ac.in https://atbiju.in/.ORCID https://orcid.org/0000-0002-0645-8261

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bicyclo[1.1.0]butanes (BCBs), featuring two fused cyclopropane rings, have found widespread application in organic synthesis. Their versatile reactivity towards radicals, nucleophiles, cations, and carbenes makes them suitable for various reactions, including ring-opening and annulation strategies. Despite this versatility, their potential as enophiles in an ene reaction remains underexplored. Considering this and given the challenges of achieving diastereoselectivity in ring-opening reactions of BCBs, herein, we present a unique method utilizing BCBs as enophiles in a mild and diastereoselective Sc(OTf)

Identifiers

PMID39118603
PMCPMC11304820

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.