Evidence map›Paper›PMID 39118288›Full record

ArticleClinical and translational medicine2024

Metastasis-enhancing protein KITENIN confers temozolomide resistance on glioblastoma with unmethylated MGMT via upregulation of cancer stem cell makers.

Eun-Jung Ahn, Yeong Jin Kim, Md Rashedunnabi Akanda, Se-Jeong Oh, Tae-Young Jung, Shin Jung, Jae-Hyuk Lee, Sung Sun Kim, Yong Yeon Jeong, Hyung-Ho Ha and 6 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. KITENIN-CCL20 axis is a potential therapeutic target for modulating immunosuppressive tumor microenvironment in glioblastoma.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Article
  5. Biodegradable nanofibrous scaffolds enhance standard of care for glioblastoma via localized targeted therapy.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Eun-Jung AhnDepartment of Neurosurgery, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South Korea.
Yeong Jin KimDepartment of Neurosurgery, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South Korea.
Md Rashedunnabi AkandaDepartment of Pathology, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South Korea.
Se-Jeong OhDepartment of Neurosurgery, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South Korea.
Tae-Young JungDepartment of Neurosurgery, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South Korea.
Shin JungDepartment of Neurosurgery, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South Korea.
Jae-Hyuk LeeDepartment of Pathology, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South Korea.
Sung Sun KimDepartment of Pathology, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South Korea.
Yong Yeon JeongDepartment of Radiology, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South Korea.
Hyung-Ho HaCollege of Pharmacy, Sunchon National University, Sunchon, South Korea.
Hoon HyunDepartment of Biomedical Sciences, Chonnam National University Medical School, Hwasun, South Korea.
Hangun KimCollege of Pharmacy, Sunchon National University, Sunchon, South Korea.
Joon Haeng RheeMedical Research Center (MRC) for Immunotherapy of Cancer, Chonnam National University Medical School, Hwasun, South Korea.
Kyung Keun KimDepartment of Pharmacology, Chonnam National University Medical School, Hwasun, South Korea.ORCID 0000-0002-7346-9526
Kyung-Hwa LeeDepartment of Pathology, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South Korea.
Kyung-Sub MoonDepartment of Neurosurgery, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South Korea.ORCID 0000-0002-1129-1064

Funding

Chonnam National University Hospital Biomedical Research Institute HCRI23010Chonnam National University Hospital Biomedical Research Institute HCRI23011National Research Foundation of Korea 2020R1A5A2031185National Research Foundation of Korea 2020R1C1C1007832National Research Foundation of Korea 2022R1A2C1011889
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA Modification MethylasesDNA Repair EnzymesDrug Resistance, NeoplasmGlioblastomaNeoplastic Stem CellsTemozolomideUp-RegulationAntineoplastic Agents, AlkylatingHumansTumor Suppressor ProteinsAntineoplastic Agents, AlkylatingDNA Modification MethylasesDNA Repair EnzymesMGMT protein, humanTemozolomideTumor Suppressor Proteins

Identifiers

PMID39118288
PMCPMC11310266

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.