Evidence map›Paper›PMID 39117971›Full record

ArticleThe Journal of antibiotics2024

Cis -decalin tetramic acid metabolite from a mangrove derived endophytic fungus Nigrospora oryzae.

Antonius R B Ola

Abstract read
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In one paragraph

Article in The Journal of antibiotics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Antonius R B OlaDepartment of Chemistry, Faculty of Science and Engineering-Universitas Nusa Cendana, Jln Adi Sucipto Penfui, Kupang, NTT, Indonesia. antonius.ola@staf.undana.ac.id.

Funding

Kementerian Riset Teknologi Dan Pendidikan Tinggi Republik Indonesia (Ministry of Research, Technology and Higher Education) SP DIPA-042061401516/2019
6 · The paper itself

Abstract

Most of the natural products containing tetramic acid have trans configuration of the decalin moiety. Undana A (1), a new cis decalin-bearing tetramic acid metabolite was isolated from endophytic fungi Nigrospora oryzae associated with Avicennia marina. The structure was determined based on the mass and NMR spectral data together with the comparison of the literature. This is the first report of cis decalin-tetramic acid metabolite from the mangrove endophytic fungus. Compound 1 was tested for cytotoxic against L5178Y mouse cancer cells and antibacterial activity against several gram-positive including MRSA and gram-negative bacteria but was found inactive.

Indexed as

Anti-Bacterial AgentsAscomycotaEndophytesMagnetic Resonance SpectroscopyPyrrolidinonesAnimalsAntineoplastic AgentsCell Line, TumorGram-Negative BacteriaGram-Positive BacteriaMiceMicrobial Sensitivity TestsNaphthalenesRhizophoraceaeAnti-Bacterial AgentsAntineoplastic AgentsdecalinNaphthalenesPyrrolidinonestetramic acid

Identifiers

PMID39117971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.