ArticleNature materials2025
Engineered nascent living human tissues with unit programmability.
Article in Nature materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- Engineering high-fidelity bone organoids: Operational classification, multilineage crosstalk, biofabrication evidence, and translational validation.Materials today. Bio · 2026Article
- Mitochondrial micro-nano reactors via enhancing mitochondrial transfer and mitophagy for alleviating metabolic crisis.Bioactive materials · 2026Article
- Fibroblast-Mimetic Lignin Polymersomes for Logic-Gated Synthesis of Mechanically Reconfigurable Bioskins.Angewandte Chemie (International ed. in English) · 2026Article
- A programmable living force sensor fabricated with surface engineered microbial network.Nature communications · 2026Article
- An Ultrasound-Responsive Bio-Adhesive Piezoelectric Hydrogel for Osteoarthritis Cartilage.Gels (Basel, Switzerland) · 2026Article
- Nascent extracellular matrix: the missing piece in hydrogel design.Cell biomaterials · 2026Article
- High-performance hydrogels in orthopedics: Structural design, performance tuning, and clinical potential.Materials today. Bio · 2026Review
- Controlling 3D Contractility via Engineered Fibrous Hydrogel Composites.Advanced functional materials · 2026Article
- Harnessing polysaccharide-mediated biomineralization for advanced bone tissue engineering.Materials today. Bio · 2026Review
- Bio-orthogonal functionalization of bacterial cellulose combining metabolic glycoengineering and click chemistry.Nature communications · 2026Article
- Rapid Generation of Fusable Cell Beads for Multi-Scale Human Living Materials Assembly.Small methods · 2026Article
- Advances in hydrogel-mediated gene therapy in ophthalmology: future directions and therapeutic potential.Regenerative biomaterials · 2026Review
- Bacteria microenvironment-responsive missile microneedles modulate immunity and penetrate biofilm for diabetic wound therapy.Bioactive materials · 2026Article
- Probiotic-Based Materials as Living Therapeutics.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Molecular tools for decoding multicellular systems: from mechanisms to medicine.National science review · 2025Review
- Fabrication of Site-Specific 3D Structures via Macroscopic Supramolecular Assembly for Spatially Controlled Alignment of Multiple Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Merging Natural Biopolymers with Supramolecular Chemistry: Emulating the Native Extracellular Matrix's Complexity.ACS nano · 2025Review
- Marine-Origin Polysaccharides and Their Chemically Modified Derivatives as Sources of Advanced Biofunctional Materials for Biomedical Applications.Biomacromolecules · 2025Review
- Sweet and sticky: increased cell adhesion through click-mediated functionalization of regenerative liver progenitor cells.Communications biology · 2025Article
- Designer mammalian living materials through genetic engineering.Bioactive materials · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Leveraging human cells as materials precursors is a promising approach for fabricating living materials with tissue-like functionalities and cellular programmability. Here we describe a set of cellular units with metabolically engineered glycoproteins that allow cells to tether together to function as macrotissue building blocks and bioeffectors. The generated human living materials, termed as Cellgels, can be rapidly assembled in a wide variety of programmable three-dimensional configurations with physiologically relevant cell densities (up to 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.