Evidence map›Paper›PMID 39117744›Full record

ArticleNeurosurgical review2024

Vestibular schwannoma microneurosurgery in patients over 70: a single institution experience and proposal of a treatment algorithm.

Silvia Michelini, Alberto Campione, Ettore Carpineta, Flavia Fraschetti, Carlo Giacobbo Scavo, Fabio Boccacci, Guglielmo Cacciotti, Giovanni Stati, Raffaelino Roperto, Amer A Alomari and 1 more

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Article in Neurosurgical review, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Silvia MicheliniDepartment of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.
Alberto CampioneDepartment of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.
Ettore CarpinetaDepartment of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.
Flavia FraschettiDepartment of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.
Carlo Giacobbo ScavoDepartment of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.
Fabio BoccacciDepartment of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.
Guglielmo CacciottiDepartment of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.
Giovanni StatiDepartment of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.
Raffaelino RopertoDepartment of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.
Amer A AlomariDepartment of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.
Luciano MastronardiDepartment of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy. mastronardinch@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElderly patients with vestibular schwannoma (VS) are commonly observed. OBJECT: Retrospective analysis of 25 patients aging ≥ 70 operated on in our neurosurgical department for unilateral VS. The purpose of our study is to propose an algorithm for the treatment of VS in elderly patients.

methodsAmerican Society of Anesthesiology (ASA) Grade I-II patients and Grade III with life-threatening tumors were enrolled. Karnofsky Performance Status Scale (KPS) was used for evalutation of the quality of life. The House-Brackmann (HB) scale for facial nerve (FN) outcome was used. Tumor size was categorized according to Koos' classification. A retrosigmoid approach was used in all cases, except one in which a translabyrinthine approach was performed. Surgical removal graduation: total (GTR), near total (NTR > 95%), subtotal (STR > 90%). The clinical and radiological follow-up period was set first at six months and then at one year after surgery. FN results evaluation was performed at one year, categorized according to House-Brackmann grades I-VI.

resultsMean age: 74,4 years (70-83); 28% ASA I, 56% ASA II, 16% ASA III. Mean tumor size: 2,7 cm (1,5-4,2 cm). GTR/NTR: 68%, STR 32%. Mortality was zero. At last follow-up (one year after surgery) FN results were: HBI 81%, HBII 9.5%, HBIII 9.5%; HB IV 0%. Only 4 patients had preoperative HB IV, of whom one improved from HB IV to HB III. Transient complications occurred only in large VS. Re-growth of residue after STR was observed in 3 cases, treated with SRS in 2 cases and observed in 1.

conclusionsAn algorithm of treatment of vestibular schwannoma in the elderly is proposed. In particular, in patients in general good conditions, age does not appear to be a major contraindication for microsurgery of VS. FN results at last follow-up are satisfactory and the complication rates are acceptable.

Indexed as

AlgorithmsMicrosurgeryNeuroma, AcousticNeurosurgical ProceduresAgedAged, 80 and overFemaleHumansMaleQuality of LifeRetrospective StudiesTreatment OutcomeAgeElderlyFacial nerveFacial nerve positionRetrosigmoid approachVestibular schwannoma

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.