Evidence map›Paper›PMID 39117675›Full record

ArticleScientific reports2024

GPER deficiency impedes murine myocutaneous revascularization and wound healing.

Randy F Ko, Oliver Q C Davidson, Michael A Ahmed, Ross M Clark, Jacquelyn S Brandenburg, Vernon S Pankratz, Geetanjali Sharma, Helen J Hathaway, Eric R Prossnitz, Thomas R Howdieshell

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. A Marine-Derived Steroid fromMarine drugs · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Randy F KoDivision of Molecular Medicine, Department of Internal Medicine, University of New Mexico Health Science Center, Albuquerque, NM, 87131, USA.
Oliver Q C DavidsonDepartment of Surgery, Augusta University/University of Georgia Medical Partnership, Athens, GA, 30602, USA.
Michael A AhmedDepartment of Surgery, Augusta University/University of Georgia Medical Partnership, Athens, GA, 30602, USA.
Ross M ClarkDepartment of Surgery, University of New Mexico Health Science Center, Albuquerque, NM, 87131, USA.
Jacquelyn S BrandenburgDepartment of Surgery, University of New Mexico Health Science Center, Albuquerque, NM, 87131, USA.
Vernon S PankratzDivision of Epidemiology, Biostatistics, and Preventive Medicine Department of Internal Medicine, University of New Mexico Health Science Center, Albuquerque, NM, 87131, USA.
Geetanjali SharmaDivision of Molecular Medicine, Department of Internal Medicine, University of New Mexico Health Science Center, Albuquerque, NM, 87131, USA.
Helen J HathawayDepartment of Cell Biology and Physiology, University of New Mexico Health Science Center, Albuquerque, NM, 87131, USA.
Eric R ProssnitzDivision of Molecular Medicine, Department of Internal Medicine, University of New Mexico Health Science Center, Albuquerque, NM, 87131, USA. eprossnitz@salud.unm.edu.
Thomas R HowdieshellDepartment of Surgery, Augusta University/University of Georgia Medical Partnership, Athens, GA, 30602, USA. thowdieshell@augusta.edu.

Funding

WOMEN'S CANCERS RESEARCH PROGRAMP30CA118100 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Yolanda Sanchez · 2005 to 2026
$57.1M
UNM HSC Clinical and Translational Science CenterUL1TR001449 · NCATS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CAMPEN, MATTHEW J, PANDHI, NANCY · 2015 to 2024
$36.9M
G protein-coupled estrogen receptor GPER and breast carcinogenesisR01CA163890 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI PROSSNITZ, ERIC R · 2012 to 2023
$3.3M
Role of GPER in Obesity and Lipid Metabolism.F31DK136330 · NIDDK · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Randy Ko · 2023 to 2026
$156k
NCATS NIH HHS UL1 TR001449NCI NIH HHS P30 CA118100NCI NIH HHS R01 CA163890NIDDK NIH HHS F31 DK136330NIH HHS CA118100NIH HHS CA163890NIH HHS F31DK136330NIH HHS UL1TR001449
6 · The paper itself

Abstract

Estrogens regulate numerous physiological and pathological processes, including wide-ranging effects in wound healing. The effects of estrogens are mediated through multiple estrogen receptors (ERs), including the classical nuclear ERs (ERα and ER

Indexed as

Mice, KnockoutNeovascularization, PhysiologicReceptors, EstrogenReceptors, G-Protein-CoupledWound HealingAnimalsFemaleIschemiaMaleMiceSkinSurgical FlapsGPER1 protein, mouseReceptors, EstrogenReceptors, G-Protein-Coupled

Identifiers

PMID39117675
PMCPMC11310200

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.