Evidence map›Paper›PMID 39117430›Full record

ArticleThe European respiratory journal2024

Genome-wide association study of susceptibility to

Boxi Lin, Jiafen Gong, Katherine Keenan, Fan Lin, Yu-Chung Lin, Julie Mésinèle, Claire Calmel, Badreddine Mohand Oumoussa, Pierre-Yves Boëlle, Loïc Guillot and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The European respiratory journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Impact of Genetics on Endocrine Manifestations of Cystic Fibrosis.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Boxi LinBiostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.ORCID https://orcid.org/0000-0003-4555-2901
Jiafen GongProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.
Katherine KeenanProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.
Fan LinProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.
Yu-Chung LinBiostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Julie MésinèleSorbonne Université, Inserm U938, Centre de Recherche Saint-Antoine (CRSA), Paris, France.
Claire CalmelSorbonne Université, Inserm U938, Centre de Recherche Saint-Antoine (CRSA), Paris, France.
Badreddine Mohand OumoussaSorbonne Université, Inserm, UMS Production et Analyse des données en Sciences de la vie et en Santé (PASS), Plateforme Post-génomique de la Pitié-Salpêtrière, Paris, France.
Pierre-Yves BoëlleSorbonne Université, Inserm, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), AP-HP, Hôpital Saint-Antoine, Paris, France.
Loïc GuillotSorbonne Université, Inserm U938, Centre de Recherche Saint-Antoine (CRSA), Paris, France.ORCID https://orcid.org/0000-0001-6853-7945
Harriet CorvolSorbonne Université, Inserm U938, Centre de Recherche Saint-Antoine (CRSA), Paris, France.ORCID https://orcid.org/0000-0002-7026-7523
Valerie WatersDivision of Infectious Diseases, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
Lei SunBiostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Lisa J StrugBiostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada lisa.strug@utoronto.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMATERIALS AND

methodsWe conducted a genome-wide association study of chronic

resultsTwo novel genome-wide significant loci with lead single nucleotide polymorphisms (SNPs) rs62369766 (chr5p12; p=1.98×10

conclusionsWe identified two novel loci that are associated with chronic

Indexed as

Cystic FibrosisGenetic Predisposition to DiseaseGenome-Wide Association StudyPolymorphism, Single NucleotidePseudomonas aeruginosaPseudomonas InfectionsAdolescentAdultCanadaChildCystic Fibrosis Transmembrane Conductance RegulatorFemaleHumansMaleMendelian Randomization AnalysisYoung AdultCystic Fibrosis Transmembrane Conductance Regulator

Identifiers

PMID39117430
PMCPMC11540985

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.