Evidence map›Paper›PMID 39117414›Full record

Observational studyBMJ open2024

What do patients with heart failure disclose about medication adherence at home to their hospital and primary care doctors? Exploratory interaction-based observational cohort study.

Christine Frigaard, Julia Menichetti, Henrik Schirmer, Herman Bjørnstad, Tone Breines Simonsen, Torbjørn Wisløff, Pål Gulbrandsen, Jennifer Gerwing

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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  3. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christine FrigaardInstitute of Clinical Medicine, University of Oslo Faculty of Medicine, Oslo, Norway christine.frigaard@medisin.uio.no.ORCID 0009-0007-3956-972X
Julia MenichettiHealth Services Research Unit, Akershus University Hospital, Lørenskog, Norway.ORCID 0000-0002-9445-987X
Henrik SchirmerInstitute of Clinical Medicine, University of Oslo Faculty of Medicine, Oslo, Norway.ORCID 0000-0002-9348-3149
Herman BjørnstadInstitute of Clinical Medicine, University of Oslo Faculty of Medicine, Oslo, Norway.
Tone Breines SimonsenHealth Services Research Unit, Akershus University Hospital, Lørenskog, Norway.ORCID 0000-0002-4103-9011
Torbjørn WisløffInstitute of Clinical Medicine, University of Oslo Faculty of Medicine, Oslo, Norway.ORCID 0000-0002-7539-082X
Pål GulbrandsenInstitute of Clinical Medicine, University of Oslo Faculty of Medicine, Oslo, Norway.ORCID 0000-0001-7434-5392
Jennifer GerwingHealth Services Research Unit, Akershus University Hospital, Lørenskog, Norway.ORCID 0000-0001-6211-8723

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe main objective of this study was twofold: to investigate what kind of information patients with heart failure (HF) tell their doctors about their medication adherence at home, and how often such information is provided in consultations where medication reconciliation is recommended. To meet these objectives, we developed an analysis to recognise, define, and count (1) patient utterances including medication adherence disclosures in clinical interactions (MADICI), (2) MADICI including red-flags for non-adherence, and (3) MADICI initiated by patients without prompts from their doctor.

designExploratory interaction-based observational cohort study. Inductive microanalysis of authentic patient-doctor consultations, audio-recorded at three time-points for each patient: (1) first ward visit in hospital, (2) discharge visit from hospital, and (3) follow-up visit with general practitioner (GP).

settingNorway (2022-2023).

participants25 patients with HF (+65 years) and their attending doctors (23 hospital doctors, 25 GPs).

resultsWe recognised MADICI by two criteria: (1) they are about medication prescribed for use at home, AND (2) they involve patients' action, experience, or stance regarding medications. Using these criteria, we identified 427 MADICIs in 25 patient trajectories: 143 (34%) at first ward visit (min-max=0-35, median=3), 57 (13%) at discharge visit (min-max=0-8, median=2), 227 (53%) at GP-visit (min-max=2-24, median=7). Of 427 MADICIs, 235 (55%) included red-flags for non-adherence. Bumetanide and atorvastatin were most frequently mentioned as problematic. Patients initiated 146 (34%) of 427 MADICIs. Of 235 'red-flag MADICIs', 101 (43%) were initiated by patients.

conclusionsSelf-managing older patients with HF disclosed information about their use of medications at home, often including red-flags for non-adherence. Patients who disclosed information that signals adherence problems tended to do so unprompted. Such disclosures generate opportunities for doctors to assess and support patients' medication adherence at home.

Indexed as

Drug MonitoringHeart FailurePhysician-Patient RelationsAgedAged, 80 and overCohort StudiesDisclosureFemaleHumansMaleMedication ReconciliationNorwayPhysicians, Primary CareDrug UtilizationHealth ServicesHeart failureHospital to Home TransitionQUALITATIVE RESEARCH

Identifiers

PMID39117414
PMCPMC11404216

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.