Evidence map›Paper›PMID 39116355›Full record

ArticleJCO precision oncology2024

Efficacy of Trametinib in Neurofibromatosis Type 1-Associated Gastrointestinal Stromal Tumors: A Case Report.

Misao Fukuda, Toru Mukohara, Takeshi Kuwata, Kuniko Sunami, Yoichi Naito

Abstract readCase Reports
In one paragraph

Article in JCO precision oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Molecular Mechanisms and Clinical Implications ofCurrent issues in molecular biology · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Misao FukudaDepartment of Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan.ORCID 0009-0000-7720-3875
Toru MukoharaDepartment of Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan.ORCID 0000-0002-8573-418X
Takeshi KuwataDepartment of Genetic Medicine and Services, National Cancer Center Hospital East, Kashiwa, Japan.
Kuniko SunamiDepartment of Laboratory Medicine, National Cancer Center Hospital, Tokyo, Japan.ORCID 0000-0002-7137-5649
Yoichi NaitoDepartment of Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan.ORCID 0000-0002-8490-9064

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trametinib, an MEK inhibitor, may offer a new therapeutic option for patients with NF1-related GIST.

Indexed as

Gastrointestinal Stromal TumorsNeurofibromatosis 1PyridonesPyrimidinonesAgedAntineoplastic AgentsFemaleGastrointestinal NeoplasmsHumansProtein Kinase InhibitorsAntineoplastic AgentsProtein Kinase InhibitorsPyridonesPyrimidinonestrametinib

Identifiers

PMID39116355
PMCPMC11371073

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.