Evidence map›Paper›PMID 39116080›Full record

ArticlePloS one2024

Transmission of SARS-CoV-2 among underserved pastoralist communities in Kajiado County, Kenya: 2020-2022.

Zipporah Macharia, Brian Ogoti, Magdaline Otieno, Pauline Gitonga, Angela Bosco-Lauth, Marybeth Maritim, Esther Lemarkoko, Aggrey Keya, Joseph Sankok, George Gitao and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zipporah MachariaInstitute of Tropical and Infectious Diseases (UNITID), University of Nairobi, Nairobi, Kenya.
Brian OgotiDepartment of Medical Microbiology and Immunology, University of Nairobi, Nairobi, Kenya.
Magdaline OtienoInstitute of Tropical and Infectious Diseases (UNITID), University of Nairobi, Nairobi, Kenya.
Pauline GitongaDepartment of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America.
Angela Bosco-LauthDepartment of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America.
Marybeth MaritimDepartment of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.
Esther LemarkokoKajiado County Referral Hospital, Kajiado Town, Kajiado, Kenya.
Aggrey KeyaKajiado County Referral Hospital, Kajiado Town, Kajiado, Kenya.
Joseph SankokKajiado County Referral Hospital, Kajiado Town, Kajiado, Kenya.
George GitaoDepartment of Pathology, Microbiology and Parasitology, University of Nairobi, Nairobi, Kenya.
Joshua OnonoDepartment of Public Health Pharmacology and Toxicology, University of Nairobi, Nairobi, Kenya.
Julius OyugiInstitute of Tropical and Infectious Diseases (UNITID), University of Nairobi, Nairobi, Kenya.
Richard A BowenDepartment of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America.ORCID 0000-0002-7576-2881

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Initial transmission of severe acute respiratory syndrome virus-2 (SARS-CoV-2) was highest in densely populated regions of Kenya. Transmission gradually trickled down to the less densely populated, remote and underserved regions such as the pastoral regions of Kajiado County which are characterized by poor healthcare systems. Molecular assays that were pivotal for COVID-19 diagnosis were not available in these regions. Serology is an alternative method for retrospectively tracking the transmission of SARS-CoV-2 in such populations. Dry blood spots (DBS) were prepared from consenting patients attending six health facilities in Kajiado County from March 2020 to March 2022. Upon elution, we conducted an enzyme-linked immunosorbent assay (ELISA) for the detection of SARS-Cov-2 IgG antibodies. Of the 908 DBSs we analyzed, 706 (78%) were from female participants. The overall seropositivity to SARS-Cov-2 antibodies was 7.3% (95% CI 5.7-9.1). The elderly (over 60 years) and male participants had a high likelihood of testing positive for SAR-CoV-2 infections. Mashuru (15.6%, 14/90) and Meto (15%, 19/127) health facilities registered the highest proportion of seropositive participants. Evidence of SARS-CoV-2 transmission among pastoralists in the remote and underserved regions of Kajiado County was established by DBS sampling and serologic testing.

Indexed as

Antibodies, ViralCOVID-19SARS-CoV-2AdolescentAdultAgedChildChild, PreschoolEnzyme-Linked Immunosorbent AssayFemaleHumansImmunoglobulin GInfantKenyaMaleMiddle AgedAntibodies, ViralImmunoglobulin G

Identifiers

PMID39116080
PMCPMC11309416

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.