Evidence map›Paper›PMID 39115941›Full record

ReviewAlzheimer's & dementia : the journal of the Alzheimer's Association2024

Design and validation of the ADNI MR protocol.

Arvin Arani, Bret Borowski, John Felmlee, Robert I Reid, David L Thomas, Jeffrey L Gunter, Lara Stables, Randy L Buckner, Youngkyoo Jung, Duygu Tosun and 3 more

Abstract readReview
In one paragraph

Review in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Arterial Spin Labeling MRI in Alzheimer's Disease: A Systematic Review of Cerebral Perfusion Biomarkers.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Pooled it
  2. Article
  3. The Cog-Aging: a 15-year cohort study of cognition in Brazilian older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  4. Reduced Effect ofNeurology. Genetics · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Characterizing Amyloid Pathogenic Spread in Alzheimer's Disease Through A Network Diffusion Model.ACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine · 2025
    Article
  19. Article
  20. Design and validation of the ADNI MR protocol.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Arvin AraniDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0001-6607-8781
Bret BorowskiDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
John FelmleeDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Robert I ReidDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
David L ThomasDepartment of Brain Repair and Rehabilitation, UCL Queen Square Institute of Neurology, University College London, London, UK.
Jeffrey L GunterDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Lara StablesDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
Randy L BucknerDepartment of Psychology, Center for Brain Science, Harvard University, Cambridge, Massachusetts, USA.
Youngkyoo JungDepartment of Biomedical Engineering, University of California Davis, Davis, California, USA.
Duygu TosunDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
Michael WeinerDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
Clifford R JackDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Alzheimer's Disease Neuroimaging Initiative

Funding

Project 1U19AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI ANDREW J SAYKIN · 2016 to 2026
$226.7M
Disease pathways in the population determined by amyloid, tau, and neurodegeneration imaging biomarkersR37AG011378 · NIA · MAYO CLINIC ROCHESTER · PI CLIFFORD R. JACK · 2018 to 2026
$6.8M
Alexander family professorship, and the GHR FoundationNIA NIH HHS R37 AG011378NIA NIH HHS U19 AG024904NIH HHS R37 AG011378NIH HHS U19AG024904
6 · The paper itself

Abstract

Phase four of the Alzheimer's Disease Neuroimaging Initiative (ADNI4) magnetic resonance imaging (MRI) protocols aim to maintain longitudinal consistency across two decades of data acquisition, while adopting new technologies. Here we describe and justify the study's design and targeted biomarkers. The ADNI4 MRI protocol includes nine MRI sequences. Some sequences require the latest hardware and software system upgrades and are continuously rolled out as they become available at each site. The main sequence additions/changes in ADNI4 are: (1) compressed sensing (CS) T1-weighting, (2) pseudo-continuous arterial spin labeling (ASL) on all three vendors (GE, Siemens, Philips), (3) multiple-post-labeling-delay ASL, (4) 1 mm

Indexed as

Alzheimer DiseaseMagnetic Resonance ImagingNeuroimagingBiomarkersBrainHumansResearch DesignBiomarkersAlzheimer's diseaseAlzheimer's Disease Neuroimaging Initiativeamyloid‐related imaging abnormalities monitoringclinical neuroimagingmagnetic resonance imaging protocolsneuroimagingpatient screening

Identifiers

PMID39115941
PMCPMC11497751

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.