Evidence map›Paper›PMID 39115741›Full record

ArticleJournal of autism and developmental disorders2025

Empathy and Autism: Establishing the Structure and Different Manifestations of Empathy in Autistic Individuals Using the Perth Empathy Scale.

Jack D Brett, David A Preece, Rodrigo Becerra, Andrew Whitehouse, Murray T Maybery

Abstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A Scoping Review on Positive Emotions and Affect in Autism.Journal of autism and developmental disorders · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jack D BrettThe University of Western Australia, Perth, Australia. jack.brett@research.uwa.edu.au.ORCID https://orcid.org/0000-0002-5022-9925
David A PreeceThe University of Western Australia, Perth, Australia.ORCID https://orcid.org/0000-0003-1060-2024
Rodrigo BecerraThe University of Western Australia, Perth, Australia.ORCID https://orcid.org/0000-0001-8286-7254
Andrew WhitehouseTelethon Kids Institute, The University of Western Australia, Perth, Australia.ORCID https://orcid.org/0000-0001-8722-1575
Murray T MayberyThe University of Western Australia, Perth, Australia.ORCID https://orcid.org/0000-0002-3760-1382

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is a common mischaracterisation that autistic individuals have reduced or absent empathy. Measurement issues may have influenced existing findings on the relationships between autism and empathy, and the structure of the empathy construct in autism remains unclear.

methodsThe present study sought to address these gaps by examining the structure and psychometric properties of the Perth Empathy Scale (PES) in autistic individuals (N = 239) compared to non-autistic individuals (N = 690).

resultsOur moderated non-linear factor analysis revealed that the multidimensional empathy construct manifested similarly in autistic and non-autistic individuals, with the PES displaying good validity and reliability. Moreover, the results revealed that autistic individuals reported reduced cognitive empathy and reduced affective empathy for positive and negative emotions. However, there was greater heterogeneity of empathic tendencies in the autistic sample, indicating that these mean differences may not be generalisable for all autistic individuals.

conclusionThe present study highlights that the PES is suitable for assessing empathy across autistic and non-autistic individuals. This work with the PES also provides greater nuance to our understanding of empathy and autism, and based on these findings, we propose the empathy heterogeneity hypothesis of autism as a new way of describing empathy in autism.

Indexed as

Autistic DisorderEmpathyAdolescentAdultChildEmotionsFemaleHumansMaleMiddle AgedPsychometricsReproducibility of ResultsSurveys and QuestionnairesYoung AdultAdultsAutism spectrum disordersEmpathyMeasurementModerated non-linear factor analysisSocial cognition and social behavior

Identifiers

PMID39115741
PMCPMC12575466

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.