Evidence map›Paper›PMID 39114856›Full record

ArticleFrontiers in pediatrics2024

Clinical characteristics of pediatric patients hospitalized with community-acquired pneumonia and cytomegalovirus DNA detected in bronchoalveolar lavage fluid.

Xinyu Wang, Yanhong Lu, Feng Chen, Linan Ruan, Lingtong Gu, Ting Wang, Heting Dong, Yuqing Wang, Chuangli Hao, Li Huang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xinyu Wang *Clinical Pediatrics School, Soochow University, Suzhou, Jiangsu, China.
Yanhong Lu *Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, Jiangsu, China.
Feng ChenDepartment of Respiratory Medicine, Luodian Hospital, Shanghai, China.
Linan RuanClinical Pediatrics School, Soochow University, Suzhou, Jiangsu, China.
Lingtong GuClinical Pediatrics School, Soochow University, Suzhou, Jiangsu, China.
Ting WangDepartment of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, Jiangsu, China.
Heting DongDepartment of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, Jiangsu, China.
Yuqing WangDepartment of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, Jiangsu, China.
Chuangli HaoDepartment of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, Jiangsu, China.
Li HuangDepartment of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, Jiangsu, China.
Yongdong YanDepartment of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, Jiangsu, China.
Huiming SunDepartment of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, Jiangsu, China.
Zhengrong ChenDepartment of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to investigate the clinical characteristics of pediatric patients hospitalized with community-acquired pneumonia (CAP) and concomitant cytomegalovirus (CMV) infection. Methods: This cross-sectional study enrolled consecutive pediatric patients admitted with CAP who tested positive for CMV DNA in bronchoalveolar lavage fluid (BALF). Flexible fiberoptic bronchoscopy was performed when routine treatment for CAP proved ineffective. The study participants were further stratified into two groups based on CMV serological test results: recent CMV infection group and CMV replication group. Clinical characteristics were compared between these two groups. Results: Among 124 patients aged 1-11 months included in this study, 80 (64.5%) patients were categorized as having recent CMV infection, and 44 (35.5%) tested positive for CMV replication. Co-infection with other pathogens was detected more frequently in the CMV replication group ( Conclusions: The CMV DNA copy numbers in blood and urine could serve as discriminatory markers between recent CMV infection and CMV replication. Measuring CMV DNA levels in blood may be an effective method for monitoring liver function impairment in pediatric patients presenting with CAP and concurrent CMV infection.

Indexed as

bloodcommunity-acquired pneumoniacytomegalovirusimmunocompetenturine

Identifiers

PMID39114856
PMCPMC11303221

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.