Evidence map›Paper›PMID 39114546›Full record

ReviewJournal of Alzheimer's disease reports2024

Clinical Heterogeneity in Alzheimer's Disease: A Possible New Amnesic Phenotype.

Carlo Abbate, Alessia Gallucci, Pietro Davide Trimarchi, Emanuela Piacquadio, Giulia Caramanti, Anna Parma, Giorgio Giulio Fumagalli, Silvia Inglese, Paola Maria Rita Parisi, Federica Tartarone and 1 more

Abstract readReview
In one paragraph

Review in Journal of Alzheimer's disease reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Carlo AbbateFondazione IRCCS Don Carlo Gnocchi, Milan, Italy.ORCID https://orcid.org/0000-0002-0368-3834
Alessia GallucciFondazione IRCCS Don Carlo Gnocchi, Milan, Italy.
Pietro Davide TrimarchiFondazione IRCCS Don Carlo Gnocchi, Milan, Italy.
Emanuela PiacquadioFondazione IRCCS Don Carlo Gnocchi, Milan, Italy.
Giulia CaramantiFondazione IRCCS Don Carlo Gnocchi, Milan, Italy.
Anna ParmaFondazione IRCCS Don Carlo Gnocchi, Milan, Italy.
Giorgio Giulio FumagalliCenter for Mind/Brain Sciences (CIMeC), University of Trento, Rovereto, Italy.
Silvia IngleseGeriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Paola Maria Rita ParisiFondazione IRCCS Don Carlo Gnocchi, Milan, Italy.
Federica TartaroneFondazione IRCCS Don Carlo Gnocchi, Milan, Italy.
Fabrizio GiuncoFondazione IRCCS Don Carlo Gnocchi, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We rediscovered a phenotype of AD known in the early 1900s as presbyophrenia, but then forgotten, and renamed as confabulation-misidentification phenotype. The phenotype includes diencephalic amnesia whose prototype is Korsakoff syndrome. The main features are anterograde and retrograde amnesia with marked disorientation and confabulation, executive impairments, reduced insight and attention deficits, misidentification, minor hallucination and other delusions, behavioral disturbances, and early anxiety. In this article, we summarize what we have discovered about the new phenotype and what is still missing to confirm this diencephalic variant of AD.

Indexed as

Alzheimer’s diseaseconfabulationdiencephalic amnesiaKorsakoff syndromemisidentificationpresbyophrenia

Identifiers

PMID39114546
PMCPMC11305845

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.