Evidence map›Paper›PMID 39114540›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2024

AI-based automated segmentation for ovarian/adnexal masses and their internal components on ultrasound imaging.

Heather M Whitney, Roni Yoeli-Bik, Jacques S Abramowicz, Li Lan, Hui Li, Ryan E Longman, Ernst Lengyel, Maryellen L Giger

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Heather M WhitneyThe University of Chicago, Department of Radiology, Chicago, Illinois, United States.ORCID https://orcid.org/0000-0002-7258-1102
Roni Yoeli-BikThe University of Chicago, Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, Chicago, Illinois, United States.ORCID https://orcid.org/0000-0002-6483-9564
Jacques S AbramowiczThe University of Chicago, Department of Obstetrics and Gynecology/Section of Ultrasound, Genetics, and Fetal Neonatal Care Center, Chicago, Illinois, United States.ORCID https://orcid.org/0000-0003-4695-5972
Li LanThe University of Chicago, Department of Radiology, Chicago, Illinois, United States.
Hui LiThe University of Chicago, Department of Radiology, Chicago, Illinois, United States.ORCID https://orcid.org/0000-0003-3139-2898
Ryan E LongmanThe University of Chicago, Department of Obstetrics and Gynecology/Section of Ultrasound, Genetics, and Fetal Neonatal Care Center, Chicago, Illinois, United States.
Ernst LengyelThe University of Chicago, Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, Chicago, Illinois, United States.ORCID https://orcid.org/0000-0001-8624-1507
Maryellen L GigerThe University of Chicago, Department of Radiology, Chicago, Illinois, United States.ORCID https://orcid.org/0000-0001-5482-9728

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI KUNLE ODUNSI · 1985 to 2026
$122.1M
RPCI-UPCI Ovarian Cancer SPOREP50CA159981 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MOYSICH, KIRSTEN B., ODUNSI, KUNLE · 2013 to 2025
$19.6M
MEDICAL IMAGING AND DATA RESOURCE CENTER (MIDRC) YEAR 375N92020D00021 · NIBIB · UNIVERSITY OF CHICAGO · PI GIGER, MARYELLEN · 2021 to 2025
$16.6M
Metabolic reprogramming of the tumor microenvironment and therapy resistanceR35CA264619 · NCI · UNIVERSITY OF CHICAGO · PI Ernst Lengyel · 2021 to 2026
$5.2M
NCI NIH HHS P30 CA014599NCI NIH HHS P50 CA159981NCI NIH HHS R35 CA264619NHLBI NIH HHS 75N92020D00021
6 · The paper itself

Abstract

Purpose: Segmentation of ovarian/adnexal masses from surrounding tissue on ultrasound images is a challenging task. The separation of masses into different components may also be important for radiomic feature extraction. Our study aimed to develop an artificial intelligence-based automatic segmentation method for transvaginal ultrasound images that (1) outlines the exterior boundary of adnexal masses and (2) separates internal components. Approach: A retrospective ultrasound imaging database of adnexal masses was reviewed for exclusion criteria at the patient, mass, and image levels, with one image per mass. The resulting 54 adnexal masses (36 benign/18 malignant) from 53 patients were separated by patient into training (26 benign/12 malignant) and independent test (10 benign/6 malignant) sets. U-net segmentation performance on test images compared to expert detailed outlines was measured using the Dice similarity coefficient (DSC) and the ratio of the Hausdorff distance to the effective diameter of the outline ( Results: The DSC (median [95% confidence interval]) was 0.91 [0.78, 0.96], and Conclusion: A combined U-net and FCM algorithm for automatic segmentation of adnexal masses and their internal components achieved excellent results compared with expert outlines and review, supporting future radiomic feature-based classification of the masses by components.

Indexed as

adnexal diseasesdeep learningmachine learningovarian cancersegmentationultrasound

Identifiers

PMID39114540
PMCPMC11301525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.