Evidence map›Paper›PMID 39114527›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2024

Lipoprotein(a): Levels and Reference Intervals Among People in Saudi Arabia.

Motasim Jawi, Hadiah Bassam Al Mahdi, Hussam Daghistani, Yousef Almoghrabi, Rami Algahtani, Dalal Tawati, Mohammed R Algethami, Yasser Noorelahi, Zuhier Awan

Abstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Motasim JawiDepartment of Physiology, College of Medicine, University of Jeddah, Jeddah, Saudi Arabia.ORCID 0000-0002-2559-9019
Hadiah Bassam Al MahdiAl Borg Medical Laboratories, Al Borg Diagnostics, Research and Development Unit, Jeddah, Saudi Arabia.ORCID 0000-0003-3483-9499
Hussam DaghistaniDepartment of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID 0000-0001-8491-8350
Yousef AlmoghrabiDepartment of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID 0000-0001-6866-1532
Rami AlgahtaniDepartment of Medicine, College of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.ORCID 0000-0002-8179-8741
Dalal TawatiDepartment of Obstetrics and Gynecology, King Abdullah Medical Complex, Jeddah, Saudi Arabia.ORCID 0000-0002-3432-3591
Mohammed R AlgethamiDepartment of Family and Community Medicine, College of Medicine, University of Jeddah, Jeddah, Saudi Arabia.ORCID 0000-0002-0554-4790
Yasser NoorelahiDepartment of Radiology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID 0009-0003-4409-6737
Zuhier AwanDepartment of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID 0000-0002-4176-335X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Blood Lp(a) concentration is recognized as an independent risk factor for cardiovascular disease (CVD). Population-based lipoprotein(a) (Lp[a]) research in Saudi Arabia is rare. Thus, the primary goal of this pilot study was to identify age- and sex-specific reference ranges for Lp(a) levels, in addition to the associations between Lp(a) levels and other atherosclerotic markers in Saudi individuals. Patients and methods: A five-year retrospective study of Lp(a) and lipid markers in Saudi patients was conducted using the Al-Borg diagnostics database (2015-2020). The population sample consisted of 361 Saudi individuals aged 18-93 years (162 males, 199 females). An immunoturbidimetric technique was used to determine Lp(a) concentration. Results: The mean and median Lp(a) levels in the study population were 35 nmol/L and 50 nmol/L, respectively. Sex and age did not influence Lp(a) values. Lp(a) values showed a minor correlation with other atherosclerotic markers when the Pearson correlation coefficient was used. In Saudi Arabia, the distribution of Lp(a) concentrations is skewed to the left, favoring lower values. Conclusion: Lp(a) levels in individuals residing in Saudi Arabia were comparable to those observed in other ethnic groups. Additionally, standardizing Lp(a) measurements according to sex and age may enhance broader applicability and facilitate comparisons across different populations. However, larger studies are required to provide more comprehensive data for comparison.

Indexed as

cardiovascular diseaselipidslipoprotein(a)reference intervalreference rangeSaudi Arabia

Identifiers

PMID39114527
PMCPMC11303827

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.