Evidence map›Paper›PMID 39114449›Full record

ArticleFASEB bioAdvances2024

Bactericidal human monoclonal antibody 1B1 shows specificity for meningococcal factor H binding protein variant 2 and displaces human factor H.

Daniele Veggi, Chelsy C Chesterman, Laura Santini, Ying Huang, Nicola Pacchiani, Jeannette Sierra, Lynn Chen, Jason Laliberte, Federica Bianchi, Roberta Cozzi and 4 more

Abstract read
In one paragraph

Article in FASEB bioAdvances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Daniele VeggiGSK Siena Italy.ORCID https://orcid.org/0000-0001-5932-3953
Chelsy C ChestermanGSK Rockville Maryland USA.ORCID https://orcid.org/0000-0003-2854-4547
Laura SantiniGSK Siena Italy.
Ying HuangGSK Rockville Maryland USA.
Nicola PacchianiGSK Siena Italy.
Jeannette SierraGSK Rockville Maryland USA.ORCID https://orcid.org/0000-0003-3174-5905
Lynn ChenGSK Rockville Maryland USA.ORCID https://orcid.org/0000-0002-2015-5638
Jason LaliberteGSK Rockville Maryland USA.ORCID https://orcid.org/0009-0006-7131-1369
Federica BianchiGSK Siena Italy.ORCID https://orcid.org/0000-0001-8957-8949
Roberta CozziGSK Siena Italy.ORCID https://orcid.org/0000-0001-7774-6167
Elisabetta FrigimelicaGSK Siena Italy.ORCID https://orcid.org/0000-0002-8173-3788
Domenico MaioneGSK Siena Italy.ORCID https://orcid.org/0000-0002-0003-3131
Matthew J BottomleyGSK Rockville Maryland USA.ORCID https://orcid.org/0000-0001-9734-5694

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thousands of disease cases and hundreds of deaths occur globally each year due to invasive meningococcal disease.

Indexed as

antibody specificityfactor‐H binding proteinmeningococcusserum bactericidal assayvaccinex‐ray structure

Identifiers

PMID39114449
PMCPMC11301264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.