Evidence map›Paper›PMID 39114302›Full record

ArticleFrontiers in oncology2024

Efficacy of novel allogeneic cancer cells vaccine to treat colorectal cancer.

George Alzeeb, Corinne Tortorelli, Jaqueline Taleb, Fanny De Luca, Benoit Berge, Chloé Bardet, Emeric Limagne, Marion Brun, Lionel Chalus, Benoit Pinteur and 4 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

George AlzeebBrenus-Pharma, Lyon, France.
Corinne TortorelliBrenus-Pharma, Lyon, France.
Jaqueline TalebImthernat, Université Claude Bernard Lyon 1, Therapies and Immune REsponse in Cancers (TIRECs), Lyon, France.
Fanny De LucaBio Elpida, Lyon, France.
Benoit BergeEuraxi, Joué-lès-Tours, France.
Chloé BardetAnaquant, Lyon, France.
Emeric LimagneTransfer Platform for Cancer Biology, Centre Georges François Leclerc, Dijon, France.
Marion BrunBrenus-Pharma, Lyon, France.
Lionel ChalusBrenus-Pharma, Lyon, France.
Benoit PinteurBrenus-Pharma, Lyon, France.
Paul BravettiBrenus-Pharma, Lyon, France.
Céline GongoraInstitut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Montpellier, France.
Lionel ApetohBrown Center for Immunotherapy, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN, United States.
Francois GhiringhelliTransfer Platform for Cancer Biology, Centre Georges François Leclerc, Dijon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) remains a significant global health burden, emphasizing the need for innovative treatment strategies. 95% of the CRC population are microsatellite stable (MSS), insensitive to classical immunotherapies such as anti-PD-1; on the other hand, responders can become resistant and relapse. Recently, the use of cancer vaccines enhanced the immune response against tumor cells. In this context, we developed a therapeutic vaccine based on Stimulated Tumor Cells (STC) platform technology. This vaccine is composed of selected tumor cell lines stressed and haptenated

Indexed as

antigenscancer vaccinecolorectal cancerhaptenationimmune responseimmunotherapyproteomicsstimulated tumor cells

Identifiers

PMID39114302
PMCPMC11303197

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.