Evidence map›Paper›PMID 39114090›Full record

ArticleACS catalysis2024

Probing Ferryl Reactivity in a Nonheme Iron Oxygenase Using an Expanded Genetic Code.

Florence J Hardy, Matthew G Quesne, Emilie F Gérard, Jingming Zhao, Mary Ortmayer, Christopher J Taylor, Hafiz S Ali, Jeffrey W Slater, Colin W Levy, Derren J Heyes and 3 more

Abstract read
In one paragraph

Article in ACS catalysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Catalytic pBiochemistry · 2026
    Article
  3. Article
  4. Article
  5. Designing Enzymatic Reactivity with an Expanded Palette.Chembiochem : a European journal of chemical biology · 2025
    Review
  6. Article
  7. Impact of Secondary Sphere Hydrogen Bonds on OJournal of the American Chemical Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Florence J HardyDepartment of Chemistry & Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.ORCID https://orcid.org/0000-0003-0671-0209
Matthew G QuesneResearch Complex at Harwell, Rutherford Appleton Laboratory, Harwell Oxford, Didcot, Oxon OX11 0FA, U.K.ORCID https://orcid.org/0000-0001-5130-1266
Emilie F GérardDepartment of Chemistry & Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.
Jingming ZhaoDepartment of Chemistry & Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.ORCID https://orcid.org/0000-0001-7104-8990
Mary OrtmayerDepartment of Chemistry & Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.ORCID https://orcid.org/0000-0002-2521-967X
Christopher J TaylorDepartment of Chemistry & Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.
Hafiz S AliDepartment of Chemistry & Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.
Jeffrey W SlaterDepartment of Chemistry and Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID https://orcid.org/0000-0002-1126-8905
Colin W LevyDepartment of Chemistry & Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.
Derren J HeyesDepartment of Chemistry & Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.ORCID https://orcid.org/0000-0002-7453-1571
J Martin BollingerDepartment of Chemistry and Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID https://orcid.org/0000-0003-0751-8585
Sam P de VisserDepartment of Chemical Engineering & Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.ORCID https://orcid.org/0000-0002-2620-8788
Anthony P GreenDepartment of Chemistry & Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.ORCID https://orcid.org/0000-0003-0454-1798

Funding

Biotechnology and Biological Sciences Research Council BB/M027023/1
6 · The paper itself

Abstract

The ability to introduce noncanonical amino acids as axial ligands in heme enzymes has provided a powerful experimental tool for studying the structure and reactivity of their Fe

Identifiers

PMID39114090
PMCPMC11301626

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.