Evidence map›Paper›PMID 39114081›Full record

ArticleHeliyon2024

Semi-quantitative analysis on sea buckthorn phenolic-rich extract coating bone-like open porous NiTi-based alloy.

Hafize Yuca, Taha Çağrı Şenocak, Oktay Yiğit, Muhammet Gökhan Albayrak, Zühal Güvenalp

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hafize YucaDepartment of Pharmacognosy, Faculty of Pharmacy, Ataturk University, 25240, Erzurum, Turkiye.
Taha Çağrı ŞenocakEngineering Faculty, Department of Metallurgical and Materials Engineering, Ataturk University, Erzurum, 25240, Turkiye.
Oktay YiğitTechnology Faculty, Department of Metallurgical and Materials Engineering, Firat University, Elazig, 23119, Turkiye.
Muhammet Gökhan AlbayrakEngineering Faculty, Department of Metallurgical and Materials Engineering, Firat University, Elazig, 23119, Turkiye.
Zühal GüvenalpDepartment of Pharmacognosy, Faculty of Pharmacy, Ataturk University, 25240, Erzurum, Turkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the feasibility of coating Ni-Ti alloy with sea buckthorn extract via a hydrothermal method for targeted delivery of beneficial phenolic compounds to bone tissue. The qualitative analysis confirmed the presence of flavonoids and tannins in sea buckthorn extract, supporting its osteogenic potential. The microhardness of the NiTi alloy substrate was suitable for biomedical applications, and successful coating was achieved without compromising its properties. NiTi alloy samples were coated with 18.1, 20.1, and 12.4 mg of extract, respectively. Comprehensive evaluations confirmed the successful integration of the extract onto the alloy's surface. The coated system exhibited sustained release properties over five days, with the highest release occurring on the first day (on average 32.1 % for the first peak and 72.1 % for the second peak), as determined by HPLC analysis. The findings demonstrate the potential of this novel approach in developing dual-functionality implants for bone health promotion. Overall, this study underscores the promising potential of Ni-Ti alloy coated with sea buckthorn extract as a targeted drug delivery system for bone tissue.

Indexed as

Bone implantHPLCNickel titanium-based alloyPhenolicsSea buckthorn

Identifiers

PMID39114081
PMCPMC11305284

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.