Evidence map›Paper›PMID 39113850›Full record

ArticleMolecular and clinical oncology2024

Successful pazopanib treatment of undifferentiated pleomorphic sarcoma with coamplification of

Haruki Matsuoka, Ken-Ichi Yoshida, Sho Nakai, Rie Suzuki, Yoshinori Imura, Haruna Takami, Makiyo Watanabe, Toru Wakamatsu, Hironari Tamiya, Hidetatsu Outani and 3 more

Abstract readCase Reports
In one paragraph

Article in Molecular and clinical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Haruki MatsuokaMusculoskeletal Oncology Service, Osaka International Cancer Institute, Osaka 541-8567, Japan.
Ken-Ichi YoshidaDepartment of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka 541-8567, Japan.
Sho NakaiMusculoskeletal Oncology Service, Osaka International Cancer Institute, Osaka 541-8567, Japan.
Rie SuzukiMusculoskeletal Oncology Service, Osaka International Cancer Institute, Osaka 541-8567, Japan.
Yoshinori ImuraDepartment of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.
Haruna TakamiDepartment of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.
Makiyo WatanabeMusculoskeletal Oncology Service, Osaka International Cancer Institute, Osaka 541-8567, Japan.
Toru WakamatsuMusculoskeletal Oncology Service, Osaka International Cancer Institute, Osaka 541-8567, Japan.
Hironari TamiyaMusculoskeletal Oncology Service, Osaka International Cancer Institute, Osaka 541-8567, Japan.
Hidetatsu OutaniDepartment of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.
Toshinari YagiMusculoskeletal Oncology Service, Osaka International Cancer Institute, Osaka 541-8567, Japan.
Shigeki KakunagaMusculoskeletal Oncology Service, Osaka International Cancer Institute, Osaka 541-8567, Japan.
Satoshi TakenakaMusculoskeletal Oncology Service, Osaka International Cancer Institute, Osaka 541-8567, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Undifferentiated pleomorphic sarcoma (UPS) is a high-grade, aggressive soft tissue sarcoma (STS) with a poor prognosis, and no definitive or effective treatment is currently available for it. Pazopanib, an orally available multiple tyrosine kinase inhibitor, has been approved for the treatment of advanced STS. The present study documents the case of a 51-year-old man with advanced UPS with coamplification of platelet-derived growth factor receptor A (

Indexed as

4q12 amplificationpazopanibPDGFRASTSUPSVEGFR2 amplification

Identifiers

PMID39113850
PMCPMC11304161

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.