Evidence map›Paper›PMID 39113494›Full record

ArticleThe Journal of neuropsychiatry and clinical neurosciences2025

Cognitive Performance of Latino and White Non-Latino Individuals With Parkinson's Disease.

Yenny Valenzuela, Kenya Luna, Ruth Uribe-Kirby, Alejandra Pawlak, Lauren Pitman, Priscilla Cuellar-Rocha, Guadalupe Romero Lucatero, Maria M Santos, Jacob D Jones

Abstract read
In one paragraph

Article in The Journal of neuropsychiatry and clinical neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yenny ValenzuelaDepartment of Psychology (all authors) and Center on Aging (Jones), California State University, San Bernardino, San Bernardino.
Kenya LunaDepartment of Psychology (all authors) and Center on Aging (Jones), California State University, San Bernardino, San Bernardino.
Ruth Uribe-KirbyDepartment of Psychology (all authors) and Center on Aging (Jones), California State University, San Bernardino, San Bernardino.
Alejandra PawlakDepartment of Psychology (all authors) and Center on Aging (Jones), California State University, San Bernardino, San Bernardino.
Lauren PitmanDepartment of Psychology (all authors) and Center on Aging (Jones), California State University, San Bernardino, San Bernardino.
Priscilla Cuellar-RochaDepartment of Psychology (all authors) and Center on Aging (Jones), California State University, San Bernardino, San Bernardino.
Guadalupe Romero LucateroDepartment of Psychology (all authors) and Center on Aging (Jones), California State University, San Bernardino, San Bernardino.
Maria M SantosDepartment of Psychology (all authors) and Center on Aging (Jones), California State University, San Bernardino, San Bernardino.
Jacob D JonesDepartment of Psychology (all authors) and Center on Aging (Jones), California State University, San Bernardino, San Bernardino.

Funding

U-RISE at CSUSBT34GM136467 · NIGMS · CALIFORNIA STATE UNIV SAN BERNARDINO · PI Leslie Renee Amodeo, Jacob D Jones · 2020 to 2026
$2.6M
Optimizing Engagement in Services for First-Episode Psychosis (FEP) in the Community Mental Health SettingK23MH119313 · NIMH · CALIFORNIA STATE UNIV SAN BERNARDINO · PI SANTOS, MARIA M · 2020 to 2024
$726k
Microbiome Composition and Function Contributes to Cognitive Impairment and Neuroinflammation in Parkinson’s DiseaseSC3NS124906 · NINDS · CALIFORNIA STATE UNIV SAN BERNARDINO · PI JONES, JACOB D · 2021 to 2024
$438k
NIGMS NIH HHS T34 GM136467NIMH NIH HHS K23 MH119313NINDS NIH HHS SC3 NS124906
6 · The paper itself

Abstract

objectiveCognitive impairment is a common nonmotor symptom in Parkinson's disease (PD). Individuals of Latino background are traditionally underrepresented in research on PD. Despite the fact that Latinos comprise 18% of the U.S. population, they commonly make up less than 5% of samples in studies of PD. Emerging evidence suggests that Latino individuals with PD may experience disparities relative to White non-Latinos in terms of having more severe motor symptoms, more severe depressive symptoms, and worse health-related quality of life. The purpose of the present study was to investigate differences in cognitive performance between Latino and White non-Latino individuals with PD and examine correlates of cognitive performance.

methodsData were obtained from the Parkinson's Progression Markers Initiative. Participants included 60 Latino individuals with PD and 1,009 White non-Latino individuals with PD, all of whom were followed annually for up to 5 years. Participants completed neuropsychological tests of attention and working memory, processing speed, visuospatial functioning, verbal fluency, and immediate and delayed memory and recall.

resultsRelative to White non-Latino individuals with PD, Latino individuals with PD had significantly lower scores on the global measure of cognitive functioning, a test of processing speed, and tests of working memory and attention. Years of education was the strongest correlate of performance in these three cognitive domains among individuals in the Latino group.

conclusionsThese findings provide initial evidence of disparities in cognitive functioning among Latino individuals with PD. Educational disadvantages may be one potential driver of these disparities.

Indexed as

Cognitive DysfunctionHispanic or LatinoParkinson DiseaseWhiteAgedFemaleHumansMaleMiddle AgedNeuropsychological TestsCognitive DisordersEducational DisadvantagesNeurodegenerative DisordersParkinson’s DiseaseRacial-Ethnic DisparitiesUnderrepresented Populations

Identifiers

PMID39113494
PMCPMC11776436

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.