Evidence map›Paper›PMID 39113422›Full record

ArticleClinical and experimental dental research2024

Genotoxicity and Micronucleus Formation as a Result of Panoramic Radiography in Epithelial Cells of the Buccal Mucosa: A Cross-sectional Study in Adults.

Nakisa Torabinia, Mojdeh Mehdizadeh, Forooz Keshani, Mohammadreza Mehdizadeh, Parisa Soltani, Gianrico Spagnuolo

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In one paragraph

Article in Clinical and experimental dental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Nakisa TorabiniaDepartment of Oral and Maxillofacial Pathology, Dental Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Mojdeh MehdizadehDepartment of Oral and Maxillofacial Radiology, Dental Implants Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Forooz KeshaniDepartment of Oral and Maxillofacial Pathology, Dental Materials Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID 0000-0001-5859-4161
Mohammadreza MehdizadehStudents Research Committee, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Parisa SoltaniDepartment of Oral and Maxillofacial Radiology, Dental Implants Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Gianrico SpagnuoloDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Naples, Italy.

Funding

The work was financially supported by Isfahan University of Medical Sciences (#3401556).
6 · The paper itself

Abstract

objectivesTo determine the genetic effects of panoramic radiography on the epithelial cells of the buccal mucosa by examining the micronucleus formation in these cells. MATERIALS AND

methodsIn this cross-sectional study, exfoliative cytology samples were prepared from the buccal mucosa of 36 patients immediately before and 10 days after panoramic radiography. The samples were prepared using liquid-based cytology with Papanicolaou staining. The slides were simultaneously evaluated by two expert pathologists and the ratio of the number of cells with micronuclei to the total number of cells on the slide was reported as a percentage. Data analysis was done using paired-samples T test, Pearson's correlation coefficient, and covariance analysis (α = 0.05).

resultsThe study sample consisted of 24 (66.67%) males and 12 females (33.33%) with a mean (SD) age of 27.36 (8.19) years. The frequency of cells with micronucleus before and after panoramic radiography was not statistically different (p = 0.468). Additionally, the frequency of micronucleated cells was not correlated with age (p = 0.737) and sex (p = 0.211).

conclusionPanoramic exposure slightly increased the frequency of cells with micronucleus in epithelial cells of the buccal mucosa. However, this increase was not statistically significant.

Indexed as

Epithelial CellsMicronucleus TestsMouth MucosaRadiography, PanoramicAdolescentAdultCross-Sectional StudiesFemaleHumansMaleMicronuclei, Chromosome-DefectiveMiddle AgedYoung Adultcytologygenotoxicitymicronucleus testpanoramic radiographyradiation

Identifiers

PMID39113422
PMCPMC11306522

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