Evidence map›Paper›PMID 39113296›Full record

ArticleCurrent medicinal chemistry2025

Construction and Biological Evaluation of Different Nanoshell Thickness Ni@SiO

Xiaomei Cheng, Chang Liu, Yuanyuan Cai, Xiangzi Li, Ruirui Zhao, Yan Feng, Meifang Wang

Abstract read
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Article in Current medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaomei ChengSchool of Pharmacy, Wannan Medical College, Institute of Synthesis and Application of Medical Materials, Wuhu, 241002, China.ORCID 0000-0001-9897-3545
Chang LiuSchool of Pharmacy, Wannan Medical College, Institute of Synthesis and Application of Medical Materials, Wuhu, 241002, China.
Yuanyuan CaiSchool of Pharmacy, Wannan Medical College, Institute of Synthesis and Application of Medical Materials, Wuhu, 241002, China.
Xiangzi LiSchool of Pharmacy, Wannan Medical College, Institute of Synthesis and Application of Medical Materials, Wuhu, 241002, China.ORCID 0000-0001-9877-7261
Ruirui ZhaoSchool of Pharmacy, Wannan Medical College, Institute of Synthesis and Application of Medical Materials, Wuhu, 241002, China.
Yan FengSchool of Pharmacy, Wannan Medical College, Institute of Synthesis and Application of Medical Materials, Wuhu, 241002, China.
Meifang WangSchool of Pharmacy, Wannan Medical College, Institute of Synthesis and Application of Medical Materials, Wuhu, 241002, China.

Funding

Academic Support Project for Reserve Candidates of Academic and Technical Leaders of Anhui Province 2019H227College Students' Innovation and Entrepreneurship Program of China 202310368044, 202210368036Key Scientific Research Projects of Wannan Medical college WK2022Z02Natural Science Foundation of Anhui province of China 2008085ME124Open Project of State Key Laboratory of Coordination Chemistry SKLCC2410Postgraduate Academic Innovation Project of Anhui Provincial of China 2022xscx131Project of Anhui Graduate Master's Studio 2022msgzs036Project of Anhui Laboratory of Molecule-based Materials fzj20006
6 · The paper itself

Abstract

backgroundNickel nanomaterials play an important role in biological applications, but they have high toxicity and poor biocompatibility. To overcome these defects, we coated the surface of Ni nanotubes with different thicknesses of SiO

objectiveThis study aimed to construct Ni nanotubes with different thicknesses of SiO

methodsMagnetic Ni nanotubes were prepared by the template-chemical deposition method. A modified version of the Stöber process was used for the SiO

resultsDifferent cell lines containing tumor cells and normal cells were used in the toxicity experiment, which confirmed the low cytotoxicity and good biocompatibility of Ni@SiO

conclusionThis work has not only provided ideas for reducing the cytotoxicity and improving the biocompatibility of biological nanomaterials, but also laid a foundation for subsequent biological applications.

Indexed as

HemoglobinsNanoshellsNanotubesNickelSilicon DioxideAdsorptionAnimalsCattleCell SurvivalHumansHemoglobinsNickelSilicon Dioxidebiocompatibilitycore-shell structure.Cytotoxicitymagnetic nanotubesprotein adsorptionsurface modification

Identifiers

PMID39113296

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.