ArticleEuropean journal of neurology2024
Remote levodopa challenge test in Parkinson's disease: Feasibility, reliability, validity and economic value.
Article in European journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed.
- Remote programming versus standard in-person programming following deep brain stimulation in patients with Parkinson's disease: a randomised controlled trial.EClinicalMedicine · 2026Article
- Effects of globus pallidus internus deep brain stimulation on freezing of gait in Parkinson's disease: a prospective short-term single-arm study.Frontiers in aging neuroscience · 2026Article
- Digital Inclusion in Parkinson's Disease: A Case-Control Study.Movement disorders clinical practice · 2025Article
- Remote levodopa challenge test in Parkinson's disease: Feasibility, reliability, validity and economic value.European journal of neurology · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
background and purposeThe aim was to demonstrate the feasibility, reliability and validity of an in-home remote levodopa challenge test (LCT), as delivered through an online platform, for patients with Parkinson's disease (PwPD).
methodsPatients with Parkinson's disease eligible for deep brain stimulation surgery screening were enrolled. Participants sequentially received an in-home remote LCT and an in-hospital standard LCT (separated by 2.71 weeks). A modified Movement Disorder Society Unified Parkinson's Disease Rating Scale Part III omitting rigidity and postural stability items was used in the remote LCT. The reliability of the remote LCT was evaluated using the intraclass correlation coefficient and the concurrent validity was evaluated using the Pearson's correlation coefficient r between the levodopa responsiveness of the remote and standard LCT.
resultsOut of 106 PwPD screened, 80 (75.5%) completed both the remote and standard LCT. There was a good reliability (intraclass correlation coefficient 0.81, 95% confidence interval 0.69-0.88) and a strong correlation (r = 0.84, 95% confidence interval 0.77-0.90) between the levodopa responsiveness of the remote and standard LCT. The mean cost for PwPD was estimated to be reduced by 91% by using the remote LCT.
conclusionThe remote LCT is feasible, reliable and valid and may reduce healthcare-related costs for PwPD and their caregivers.
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Registered trials
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