Evidence map›Paper›PMID 39113017›Full record

ArticleRespiratory research2024

Effects of increasing tidal volume and end-expiratory lung volume on induced bronchoconstriction in healthy humans.

Alessandro Gobbi, Andrea Antonelli, Raffaele Dellaca, Giulia M Pellegrino, Riccardo Pellegrino, Jeffrey J Fredberg, Julian Solway, Vito Brusasco

Abstract read
In one paragraph

Article in Respiratory research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. The importance of mechanical forces in chronic respiratory diseases.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alessandro GobbiDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milano, 20133, Italy.
Andrea AntonelliAllergologia e Fisiopatologia Respiratoria, ASO S. Croce e Carle, 12100, Cuneo, Italy.
Raffaele DellacaDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milano, 20133, Italy. raffaele.dellaca@polimi.it.
Giulia M PellegrinoCasa di Cura del Policlinico, Dipartimento di Scienze Neuroriabilitative, Milano, Italy.
Riccardo PellegrinoCentro Medico Pneumologico Torino, 10129, Torino, Italy.
Jeffrey J FredbergHarvard T. H. Chan School of Public Health, Harvard University, Boston, MA, 02115, USA.
Julian SolwayDepartment of Medicine, University of Chicago, Chicago, IL, USA.
Vito BrusascoDipartimento di Medicina Sperimentale, Università di Genova, 16132, Genova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreasing functional residual capacity (FRC) or tidal volume (V

methodsNineteen healthy volunteers were challenged with a single-dose of MCh and forced oscillation was used to measure inspiratory resistance at 5 and 19 Hz (R

resultsTripling V

conclusionsThese data show that increasing FRC and V

Indexed as

BronchoconstrictionMethacholine ChlorideTidal VolumeAdultAirway ResistanceBronchial Provocation TestsBronchoconstrictor AgentsFemaleForced Expiratory VolumeFunctional Residual CapacityHealthy VolunteersHumansLungMaleYoung AdultBronchoconstrictor AgentsMethacholine ChlorideAirway caliberLung volumeMethacholineOscillometryTidal breathing

Identifiers

PMID39113017
PMCPMC11304934

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.