ArticleNature2024
DNA-sensing inflammasomes cause recurrent atherosclerotic stroke.
Abstract read
In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cell-Free Nucleic Acids for Early Diagnosis of Acute Ischemic Stroke: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2025Pooled it
- Timing-dependent anti-inflammatory effects of empagliflozin in monocyte-derived macrophages from post-myocardial infarct patients with type 2 diabetes.Cardiovascular diabetology · 2026Trial
- Oxidative stress in neurodegeneration: from a simple insult to a dynamic regulator.Redox report : communications in free radical research · 2026Review
- A roadmap towards clinical use of molecular biomarkers in acute ischaemic stroke.Nature reviews. Neurology · 2026Review
- Review
- Extracellular Vesicle Packaged TDP43 Derived From ECs Exacerbates Cigarette Tar-Related Atherosclerosis Progression via Enhancing Macrophage Extracellular Traps.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Spatially Distinct Bone Marrow Sites Are Asymmetrically Impacted by Inflammatory Cardiovascular Disease.JACC. Basic to translational science · 2026Article
- TRIM28 SUMOylates IRF3 in astrocytes to drive neutrophils infiltration and ischemic cerebral injury.Cell death and differentiation · 2026Article
- Emerging evidence of neutrophil extracellular traps in essential hypertension and target organ damage: pathophysiological insights and therapeutic implications.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Review
- DNA-triggered AIM2 condensation orchestrates immune activation and regulation.Protein & cell · 2026Article
- Advancing the applications of liquid biopsies in oncology.Nature reviews. Genetics · 2026Review
- The NETs-cGAS-STING Axis in Ischemic Stroke: Linking Neutrophil-Microglia Crosstalk, Immunothrombosis, and Neuroinflammation.Molecular neurobiology · 2026Review
- Stroke Heart Syndrome: Neuroimmune and Metabolic Crosstalk with Conceptual Approaches for Precision Therapeutics.Cardiovascular drugs and therapy · 2026Review
- Functional Heterogeneity of Immune Cell Subpopulations in Atherosclerosis: From Basic Mechanisms to Precision Therapy.Reviews in cardiovascular medicine · 2026Review
- A 'Tangled Web' in the CNS: unraveling neutrophil extracellular traps in neurological disorders.Molecular neurodegeneration · 2026Review
- Vascular Aging.Circulation · 2026Review
- Mechanisms and therapeutic potential of colchicine in atherosclerotic cardiovascular disease.Nature cardiovascular research · 2026Review
- Identifying the role of NLRP3 inflammasome in stroke progression and outcome before recanalization.Cell reports. Medicine · 2026Article
- The IL-1β/NETs/AIM2 axis participates in the formation of trauma-induced heterotopic ossification by orchestrating crosstalk between neutrophils and macrophages.Journal of advanced research · 2026Article
- Early post-transplant recipient tissue injury predicts allograft function, rejection and survival in lung transplant recipients: evidence from cell-free DNA.The European respiratory journal · 2026Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
34 authors.
Jiayu Cao *Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0002-8826-2595
Stefan Roth *Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany. stefan.roth@med.uni-muenchen.de.ORCID 0000-0001-6823-2981
Sijia ZhangInstitute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany.
Anna KopczakInstitute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0002-5037-2342
Samira MamiInstitute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany.
Yaw AsareInstitute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0002-8946-5650
Marios K GeorgakisInstitute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0003-3507-3659
Denise MessererMedizinische Klinik und Poliklinik I, LMU University Hospital, LMU Munich, Munich, Germany.
Amit HornDepartment of Developmental Biology and Cancer Research, Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem, Israel.
Ruth ShemerDepartment of Developmental Biology and Cancer Research, Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem, Israel.
Charlene JacqmarcqNormandie University, UNICAEN, INSERM UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), GIP Cyceron, Institute Blood and Brain @ Caen-Normandie (BB@C), Caen, France.
Audrey PicotNormandie University, UNICAEN, INSERM UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), GIP Cyceron, Institute Blood and Brain @ Caen-Normandie (BB@C), Caen, France.
Jack P GreenGeoffrey Jefferson Brain Research Centre, The Manchester Academic Health Science Centre, Northern Care Alliance NHS Group, University of Manchester, Manchester, UK.ORCID 0000-0003-1108-3422
Christina SchleglInstitute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0001-7314-5954
Xinghai LiDepartment of Cardiology, German Heart Centre Munich, Technical University of Munich, Munich, Germany.
Lukas TomasMedizinische Klinik und Poliklinik I, LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0001-9371-8721
Alexander DutschDepartment of Cardiology, German Heart Centre Munich, Technical University of Munich, Munich, Germany.
Thomas G LimanCenter for Stroke Research Berlin (CSB), Charité-Universitätsmedizin Berlin, Berlin, Germany.
Matthias EndresCenter for Stroke Research Berlin (CSB), Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0001-6520-3720
Saskia R WernsdorfInstitute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany.
Christina FürleInstitute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany.
Olga CarofiglioInstitute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0001-8358-7414
Jie ZhuInstitute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany.
David BroughGeoffrey Jefferson Brain Research Centre, The Manchester Academic Health Science Centre, Northern Care Alliance NHS Group, University of Manchester, Manchester, UK.ORCID 0000-0002-2250-2381
DEMDAS Study Group
Veit HornungGene Center and Department of Biochemistry, LMU Munich, Munich, Germany.ORCID 0000-0002-4150-194X
Martin DichgansInstitute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0002-0654-387X
Denis VivienNormandie University, UNICAEN, INSERM UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), GIP Cyceron, Institute Blood and Brain @ Caen-Normandie (BB@C), Caen, France.ORCID 0000-0002-7636-2185
Christian SchulzMedizinische Klinik und Poliklinik I, LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0002-8149-0747
Yuval DorDepartment of Developmental Biology and Cancer Research, Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem, Israel.ORCID 0000-0003-2456-2289
Steffen TiedtInstitute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0002-8817-8457
Hendrik B SagerDepartment of Cardiology, German Heart Centre Munich, Technical University of Munich, Munich, Germany.
Gerrit M GrosseDepartment of Neurology, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-5335-9880
Arthur LieszInstitute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany. arthur.liesz@med.uni-muenchen.de.ORCID 0000-0002-9069-2594
Funding
Medical Research Council MR/T016515/1Vascular Dementia Research Foundation, the European Research Council
Abstract
The risk of early recurrent events after stroke remains high despite currently established secondary prevention strategies
Indexed as
AtherosclerosisInflammasomesPlaque, AtheroscleroticRecurrenceStrokeAdultAnimalsCell-Free Nucleic AcidsDeoxyribonucleasesDisease Models, AnimalDNA-Binding ProteinsExtracellular TrapsFemaleHumansInflammationMaleAIM2 protein, humanAim2 protein, mouseCell-Free Nucleic AcidsDeoxyribonucleasesDNA-Binding ProteinsInflammasomes
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.