ArticleNature2024
The ribosome lowers the entropic penalty of protein folding.
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Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24citing papers in PubMed
–field-weighted citation impact
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Who cites it
24 citing papers in PubMed.
- Quasi-continuous cotranslational compaction and folding of a multidomain protein.Nature communications · 2026Article
- A detailed molecular picture of protein folding during active translation.bioRxiv : the preprint server for biology · 2026Article
- Genetically Encoded Pentafluorophenylalanine Enables Quantitative Probing of Local Protein Malleability by 19F NMR.Journal of the American Chemical Society · 2026Article
- Evolution of the ribosomal exit tunnel through the eyes of the nascent chain.Nucleic acids research · 2026Article
- Structures of protein folding intermediates on the ribosome.Nature structural & molecular biology · 2026Article
- Nascent protein retention at polysomes reduces kinetic barriers to self-assembly.bioRxiv : the preprint server for biology · 2026Article
- Transient tertiary structure in intrinsically disordered proteins revealed by multithermal enhanced sampling.Nature communications · 2026Article
- How Does Genetic Information Enable Life?Bulletin of mathematical biology · 2026Article
- NAC promotes co-translational protein folding at the ribosomal tunnel exit.Molecular cell · 2026Article
- Article
- Approaches to Study Proteins Encoded by Essential Genes.Proteins · 2026Review
- Measuring and locating the changes in protein structure using MELO.Nature communications · 2026Article
- Mechanistic Insights into Protein Biogenesis and Maturation on the Ribosome.Journal of molecular biology · 2025Review
- GroEL/ES chaperonin unfolds then encapsulates a nascent protein on the ribosome.Nature communications · 2025Article
- The human ribosome modulates multidomain protein biogenesis by delaying cotranslational domain docking.Nature structural & molecular biology · 2025Article
- Structure and Dynamics of the Misfolding Intermediate in the Pathogenic T183A Prion Protein Mutant.Journal of chemical theory and computation · 2025Article
- Refolding of the Alkali Denatured Bovine Beta-Lactoglobulin by the Synthetic ZnO Nanochaperone: A Useful Technique for Protein Renaturation.ACS omega · 2025Article
- Cotranslational protein folding through non-native structural intermediates.Science advances · 2025Article
- Advances in the chemical synthesis of human proteoforms.Science China. Life sciences · 2025Review
- Trigger factor accelerates nascent chain compaction and folding.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
Corrections and comments
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Authors and funding
14 authors.
Julian O Streit *Institute of Structural and Molecular Biology, Department of Structural and Molecular Biology, University College London, London, UK.ORCID 0000-0001-6114-3636
Ivana V Bukvin *Institute of Structural and Molecular Biology, Department of Structural and Molecular Biology, University College London, London, UK.ORCID 0000-0003-1429-9245
Sammy H S Chan *Institute of Structural and Molecular Biology, Department of Structural and Molecular Biology, University College London, London, UK. s.chan.12@ucl.ac.uk.ORCID 0000-0003-1156-1818
Shahzad BashirInstitute of Structural and Molecular Biology, Department of Structural and Molecular Biology, University College London, London, UK.
Lauren F WoodburnInstitute of Structural and Molecular Biology, Department of Structural and Molecular Biology, University College London, London, UK.
Tomasz WłodarskiInstitute of Structural and Molecular Biology, Department of Structural and Molecular Biology, University College London, London, UK.
Angelo Miguel FigueiredoInstitute of Structural and Molecular Biology, Department of Structural and Molecular Biology, University College London, London, UK.ORCID 0000-0001-7039-5341
Gabija JurkeviciuteInstitute of Structural and Molecular Biology, Department of Structural and Molecular Biology, University College London, London, UK.
Haneesh K SidhuInstitute of Structural and Molecular Biology, Department of Structural and Molecular Biology, University College London, London, UK.
Charity R HornbyInstitute of Structural and Molecular Biology, Department of Structural and Molecular Biology, University College London, London, UK.
Christopher A WaudbyInstitute of Structural and Molecular Biology, Department of Structural and Molecular Biology, University College London, London, UK.ORCID 0000-0001-7810-3753
Lisa D CabritaInstitute of Structural and Molecular Biology, Department of Structural and Molecular Biology, University College London, London, UK.ORCID 0000-0003-2963-8078
Anaïs M E CassaignauInstitute of Structural and Molecular Biology, Department of Structural and Molecular Biology, University College London, London, UK. anais.cassaignau.09@alumni.ucl.ac.uk.ORCID 0000-0003-3963-082X
John ChristodoulouInstitute of Structural and Molecular Biology, Department of Structural and Molecular Biology, University College London, London, UK. j.christodoulou@ucl.ac.uk.ORCID 0000-0002-6710-3843
Funding
Wellcome Trust FC001029
Abstract
Most proteins fold during biosynthesis on the ribosome
Indexed as
EntropyProtein BiosynthesisProtein FoldingProteinsRibosomesModels, MolecularMutationNuclear Magnetic Resonance, BiomolecularProtein ConformationProtein RefoldingProtein StabilityProtein UnfoldingSolubilityProteins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.