Evidence map›Paper›PMID 39112667›Full record

ArticleScientific reports2024

Safety evaluation of Indocalamus Iatifolius McClure leaves based on acute toxicity, harmful metals, and 9 organochlorine residue determination.

Miyan Liu, Xiaofen Li, Xiangpei Wang, Lingling Zhang, Xiaosong Yang, Xianyou Yang, Hongmei Wu

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miyan Liu *Guizhou University of Traditional Chinese Medicine, Guiyang, 550025, China.
Xiaofen Li *Guizhou University of Traditional Chinese Medicine, Guiyang, 550025, China.
Xiangpei WangGuizhou Minzu University, Guiyang, 550025, China.
Lingling ZhangGuizhou University of Traditional Chinese Medicine, Guiyang, 550025, China.
Xiaosong YangGuizhou University of Traditional Chinese Medicine, Guiyang, 550025, China.
Xianyou YangGuizhou Kanong Cloud Service Co., Ltd., Zhenfeng Guizhou, 562200, China.
Hongmei WuGuizhou University of Traditional Chinese Medicine, Guiyang, 550025, China. 381176659@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the safety of Indocalamu Iatifolius McClur leaves sold in the market, a study was conducted using Indocalamu Iatifolius McClur leaves randomly collected from an online store and a large supermarket. Acute toxicity experiments were performed on mice, and their body weight was monitored for 14 days after administration. After the observation period, blood samples were collected for biochemical analysis, and organ pathology was examined. Then, the content of copper (Cu), lead (Pb), cadmium (Cd), mercury (Hg), arsenic (As), and the residues of nine organochlorine pesticides in Indocalamu Iatifolius McClur leaves were measured according to the National Food Safety Standard (GB/T5009-2003) and the pesticide residue determination methods in the 2020 edition of the Chinese Pharmacopoeia. The results showed that the mice in the Indocalamu Iatifolius McClur leaves (online store) group experienced mortality and severe liver and lung damage. The levels of lead, cadmium, mercury, arsenic, and the nine organochlorine pesticides met the relevant standards and regulations. However, the copper content in the Indocalamu Iatifolius McClur leaves (online store) group was nearly 80 times higher than that in the supermarket group. Mice in the Indocalamu Iatifolius McClur leaves (supermarket) group remained healthy without any abnormalities, and the levels of harmful metals and organochlorine pesticides complied with the standards and regulations. The study suggests the need for regulatory policies and safety standards for the sale of Indocalamu Iatifolius McClur leaves.

Indexed as

Hydrocarbons, ChlorinatedPesticide ResiduesPlant LeavesAnimalsFemaleMaleMetals, HeavyMiceToxicity Tests, AcuteHydrocarbons, ChlorinatedMetals, HeavyPesticide ResiduesAcute toxicityBlood biochemistryHistopathologyIndocalamu Iatifolius McClur leavesMetalsOrganochlorine pesticides

Identifiers

PMID39112667
PMCPMC11306345

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.